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Category:GO:0071507 ! pheromone response MAPK cascade
name: pheromone response MAPK cascade
namespace: biological_process
def: "A MAPK cascade containing at least the Fus3 MAP kinase. It starts with the activation of Ste20, a MAP4K, which activates Ste11, a MAP3K, which in turn activate Ste7, a MAP2K, which activates Fus3. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. This MAPK cascade is triggered by a pheromone activating its G protein-coupled receptor, and results in cellular responses that lead to conjugation with cellular fusion." [GOC:mah, GOC:vw, PMID:17604854]
synonym: "conjugation with cellular fusion, MAPKKK cascade" EXACT [GOC:mah]
synonym: "Fus3 signaling cascade" NARROW [PMID:20880736]
synonym: "MAPK cascade involved in conjugation with cellular fusion" EXACT []
synonym: "MAPK signaling in response to pheromone" RELATED [PMID:20880736]
synonym: "MAPKKK cascade involved in conjugation with cellular fusion" EXACT [GOC:signaling]
synonym: "MAPKKK cascade involved in mating response" RELATED [GOC:mah]
synonym: "pheromone MAPK module" RELATED [PMID:20880736]
is_a: GO:0000165 ! MAPK cascade
relationship: part_of: GO:0000747 ! conjugation with cellular fusion
relationship: part_of: GO:0000750 ! pheromone-dependent signal transduction involved in conjugation with cellular fusion
intersection_of: GO:0000165 ! MAPK cascade
intersection_of: part_of GO:0000747 ! conjugation with cellular fusion
AmiGO
<GOterm>GO:0071507</GOterm>
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