Category:GO:0051976 ! lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate

name: lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine." [MetaCyc:PWY-3081]
synonym: "lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate" EXACT []
synonym: "lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate" EXACT []
xref: MetaCyc:PWY-3081
is_a: GO:0019878 ! lysine biosynthetic process via aminoadipic acid

AmiGO <GOterm>GO:0051976</GOterm>
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