Category:GO:0044823 ! retroviral integrase activity

name: retroviral integrase activity
namespace: molecular_function
def: "Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism." [PMID:19091057]
is_a: GO:0008907 ! integrase activity
relationship: part_of: GO:0044826 ! viral genome integration into host DNA

AmiGO <GOterm>GO:0044823</GOterm>
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