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Category:GO:0038157 ! granulocyte-macrophage colony-stimulating factor signaling pathway
name: granulocyte-macrophage colony-stimulating factor signaling pathway
namespace: biological_process
def: "The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors." [GOC:nhn, GOC:signaling, PMID:17027509]
synonym: "CSF2 signaling pathway" EXACT [PR:000005931]
synonym: "GM-CSF receptor signaling pathway" EXACT [GOC:nhn]
synonym: "GM-CSF signaling pathway" EXACT [PR:000005931]
synonym: "granulocyte-macrophage colony-stimulating factor receptor signaling pathway" EXACT [GOC:nhn]
synonym: "granulocyte-macrophage colony-stimulating factor signalling pathway" RELATED [GOC:bf]
is_a: GO:0019221 ! cytokine-mediated signaling pathway
AmiGO
<GOterm>GO:0038157</GOterm>
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