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Category:GO:0038060 ! nitric oxide-cGMP-mediated signaling
name: nitric oxide-cGMP-mediated signaling
namespace: biological_process
def: "An intracellular signaling cassette in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP." [GOC:signaling, PMID:21549190, PMID:22019632]
synonym: "canonical nitric oxide signaling" EXACT [GOC:bf]
synonym: "classical nitric oxide signaling" EXACT [PMID:21549190]
synonym: "nitric oxide-cGMP-mediated signal transduction" EXACT []
synonym: "nitric oxide-cGMP-mediated signaling pathway" EXACT []
synonym: "nitric oxide-cGMP-mediated signalling pathway" EXACT [GOC:mah]
synonym: "NO-cGMP signaling pathway" EXACT [PMID:22019632]
is_a: GO:0007263 ! nitric oxide mediated signal transduction
is_a: GO:0019934 ! cGMP-mediated signaling
AmiGO
<GOterm>GO:0038060</GOterm>
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