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Category:GO:0036513 ! Derlin-1 retrotranslocation complex
name: Derlin-1 retrotranslocation complex
namespace: cellular_component
def: "A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel." [GOC:bf, GOC:PARL, PMID:15215856, PMID:16186510]
comment: The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.
synonym: "Derlin-1 complex" EXACT [PMID:18555783]
synonym: "Derlin-1 protein dislocation complex" EXACT [PMID:18555783]
synonym: "Derlin-1 retro-translocation complex" EXACT [GOC:bf]
synonym: "Derlin-1 retrotranslocon" EXACT [GOC:bf]
synonym: "ERAD protein dislocation complex" EXACT [PMID:18555783]
is_a: GO:0098796 ! membrane protein complex
is_a: GO:0140534 ! endoplasmic reticulum protein-containing complex
relationship: part_of: GO:0005789 ! endoplasmic reticulum membrane
AmiGO
<GOterm>GO:0036513</GOterm>
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