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Category:GO:0035695 ! mitophagy by internal vacuole formation
name: mitophagy by internal vacuole formation
namespace: biological_process
def: "The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes." [GOC:autophagy, GOC:bf, GOC:sp, PMID:21264228]
comment: In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.
synonym: "MIV-mediated mitophagy" NARROW [PMID:21264228]
is_a: GO:0000422 ! autophagy of mitochondrion
AmiGO
<GOterm>GO:0035695</GOterm>
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