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Category:GO:0033596 ! TSC1-TSC2 complex
name: TSC1-TSC2 complex
namespace: cellular_component
def: "A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway." [PMID:10585443, PMID:17121544, PMID:9580671]
synonym: "tuberin-hamartin complex" EXACT []
synonym: "tuberous sclerosis complex" EXACT []
is_a: GO:0032991 ! protein-containing complex
relationship: part_of: GO:0005829 ! cytosol
AmiGO
<GOterm>GO:0033596</GOterm>
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