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Category:GO:0019243 ! methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
name: methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step." [GOC:ai, GOC:dph, PMID:2198020]
synonym: "D-lactate biosynthesis from methylglyoxal" BROAD []
synonym: "D-lactate biosynthetic process from methylglyoxal" BROAD []
synonym: "glyoxalase system" RELATED []
synonym: "methylglyoxal breakdown to D-lactate" BROAD []
synonym: "methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione" EXACT []
synonym: "methylglyoxal degradation to D-lactate" BROAD []
synonym: "methylglyoxal detoxification" RELATED []
xref: MetaCyc:PWY-5386
is_a: GO:0061727 ! methylglyoxal catabolic process to lactate
relationship: has_part: GO:0004416 ! hydroxyacylglutathione hydrolase activity
relationship: has_part: GO:0004462 ! lactoylglutathione lyase activity
AmiGO
<GOterm>GO:0019243</GOterm>
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