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Category:GO:0016272 ! prefoldin complex
name: prefoldin complex
namespace: cellular_component
def: "A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics." [GOC:jl, PMID:17384227, PMID:24068951, PMID:9630229]
synonym: "GIM complex" NARROW []
xref: Wikipedia:Prefoldin
is_a: GO:0032991 ! protein-containing complex
AmiGO
<GOterm>GO:0016272</GOterm>
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