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Category:GO:0009922 ! fatty acid elongase activity
name: fatty acid elongase activity
namespace: molecular_function
def: "Catalysis of the reaction: a very-long-chain acyl-CoA + H+ + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA. This reaction is the first (condensation) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit." [PMID:16564093, PMID:19763486, RHEA:32727]
synonym: "condensing enzyme" BROAD []
synonym: "elongation of very long chain fatty acids activity" EXACT []
synonym: "ELOVL" EXACT []
synonym: "very-long-chain 3-ketoacyl-CoA synthase" EXACT []
synonym: "very-long-chain 3-oxoacyl-CoA synthase" EXACT []
synonym: "very-long-chain beta-ketoacyl-CoA synthase" EXACT []
xref: EC:2.3.1.199
xref: MetaCyc:RXN-7697
xref: RHEA:32727
is_a: GO:0016747 ! acyltransferase activity, transferring groups other than amino-acyl groups
AmiGO
<GOterm>GO:0009922</GOterm>
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