Category:GO:0008123 ! cholesterol 7-alpha-monooxygenase activity

id: GO:0008123

name: cholesterol 7-alpha-monooxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha-hydroxycholesterol + H+ + H2O + oxidized [NADPH--hemoprotein reductase]." [RHEA:21812]
synonym: "cholesterol 7-alpha-hydroxylase activity" EXACT []
synonym: "cholesterol 7alpha-hydroxylase activity" RELATED [EC:1.14.14.23]
synonym: "cholesterol 7alpha-monooxygenase activity" RELATED [EC:1.14.14.23]
synonym: "cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)" RELATED [EC:1.14.14.23]
synonym: "cytochrome P450 CYP7A1" NARROW []
xref: EC:1.14.14.23
xref: MetaCyc:CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN
xref: RHEA:21812
is_a: GO:0008387 ! steroid 7-alpha-hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

AmiGO <GOterm>GO:0008123</GOterm>
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