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Category:GO:0004739 ! pyruvate dehydrogenase (acetyl-transferring) activity
name: pyruvate dehydrogenase (acetyl-transferring) activity
namespace: molecular_function
def: "Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2." [EC:1.2.4.1]
synonym: "MtPDC (mitochondrial pyruvate dehydogenase complex) activity" NARROW [EC:1.2.4.1]
synonym: "PDH" RELATED [EC:1.2.4.1]
synonym: "pyruvate dehydrogenase (lipoamide) activity" EXACT []
synonym: "pyruvate dehydrogenase complex activity" RELATED [EC:1.2.4.1]
synonym: "pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)" RELATED [EC:1.2.4.1]
synonym: "pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity" RELATED [EC:1.2.4.1]
xref: EC:1.2.4.1
xref: MetaCyc:RXN0-1134
xref: RHEA:19189
is_a: GO:0004738 ! pyruvate dehydrogenase activity
is_a: GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AmiGO
<GOterm>GO:0004739</GOterm>
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