Category:GO:0002927 ! archaeosine-tRNA biosynthetic process

name: archaeosine-tRNA biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs." [GOC:hjd, PMID:20129918]
comment: Archaeosine (7-formamidino-7-deazaguanosine) is a structural variant of the hypermodified nucleoside 7-deazaguanosine. The biosynthesis pathway starts with archaeosine tRNA-guanine transglycosylase (ArcTGT) which catalyzes the exchange of guanine at position 15 in the D-loop of archaeal tRNAs with a free 7-cyano-7-deazaguanine.
is_a: GO:0006400 ! tRNA modification
is_a: GO:0009058 ! biosynthetic process
relationship: has_part: GO:0002948 ! archaeosine synthase activity
relationship: has_part: GO:0043867 ! 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity

AmiGO <GOterm>GO:0002927</GOterm>
Gene Ontology Home