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Category:GO:0002432 ! granuloma formation
name: granuloma formation
namespace: biological_process
def: "The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic." [GO_REF:0000022, GOC:add, ISBN:068340007X, ISBN:0721601464, ISBN:081533642X]
is_a: GO:0002252 ! immune effector process
relationship: part_of: GO:0002544 ! chronic inflammatory response
AmiGO
<GOterm>GO:0002432</GOterm>
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