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Category:GO:0002255 ! tissue kallikrein-kinin cascade
name: tissue kallikrein-kinin cascade
namespace: biological_process
def: "A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability." [GOC:add, PMID:11842287, PMID:14501145]
synonym: "glandular kallikrein-kinin cascade" EXACT []
is_a: GO:0002254 ! kinin cascade
AmiGO
<GOterm>GO:0002255</GOterm>
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