name: B-1 B cell differentiation
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def: "The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity." [GOC:add, ISBN:0781735149]
synonym: "B-1 B cell development" RELATED [GOC:add]
synonym: "B-1 B lymphocyte differentiation" EXACT 
synonym: "B-1 B-cell differentiation" EXACT 
synonym: "B-1 B-lymphocyte differentiation" EXACT 
is_a: GO:0002335 ! mature B cell differentiation
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Pages in category "GO:0001923 ! B-1 B cell differentiation"
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