name: cell cycle checkpoint signaling
The contents of this box are automatically generated. You can help by adding information to the "Notes"
def: "A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." [GOC:mtg_cell_cycle]
comment: This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.
synonym: "cell cycle checkpoint" EXACT 
synonym: "G1/S checkpoint" NARROW 
synonym: "G1/S transition checkpoint" NARROW 
synonym: "G2/M checkpoint" NARROW 
synonym: "G2/M transition checkpoint" NARROW 
synonym: "signal transduction involved in cell cycle checkpoint" EXACT 
synonym: "signal transduction involved in G2/M transition checkpoint" EXACT 
is_a: GO:0035556 ! intracellular signal transduction
is_a: GO:1901988 ! negative regulation of cell cycle phase transition
intersection_of: GO:0035556 ! intracellular signal transduction
intersection_of: negatively_regulates GO:0044770 ! cell cycle phase transition
Gene Ontology Home
See Help:References for how to manage references in GONUTS.
This category has the following 6 subcategories, out of 6 total.