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CVMA5:VEMP
Contents
| Species (Taxon ID) | Murine coronavirus (strain A59) (MHV-A59) (Murine hepatitis virus). (11142) | |
| Gene Name(s) | E (synonyms: sM) | |
| Protein Name(s) | Envelope small membrane protein
E protein sM protein Non-structural protein NS3 | |
| External Links | ||
| UniProt | P0C2R0 | |
| EMBL | AF029248 | |
| RefSeq | NP_068673.1 | |
| TCDB | 1.A.65.1.1 | |
| GeneID | 1489755 | |
| Proteomes | UP000007192 | |
| GO | GO:0044178 GO:0016021 GO:0019031 GO:0055036 GO:0006915 | |
| InterPro | IPR003873 | |
| Pfam | PF02723 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0044662 |
disruption by virus of host cell membrane |
ECO:0000314 |
P |
Figure 2A. Shows, that E is a protein that increases permeabilization of the cell membrane to hygromycin B (an antibiotic that inhibits protein synthesis). The gels in the figure show the amount of protein synthesis, in cells that express E, as an indicator of the amount of hygromycin B able to enter the cell. BFA interferes with the operations of the Golgi and hinders the transport of synthesized proteins to the membrane. The presence of BFA in this assay decreased the permeabilization, which is evident from the increased protein synthesis shown on the gel. |
complete | |||||
|
involved_in |
GO:0046760 |
viral budding from Golgi membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044662 |
disruption by virus of host cell membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033644 |
host cell membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044177 |
host cell Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044178 |
host cell Golgi membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Madan, V et al. (2005) Viroporin activity of murine hepatitis virus E protein. FEBS Lett. 579 3607-12 PubMed GONUTS page
- ↑ Raamsman, MJ et al. (2000) Characterization of the coronavirus mouse hepatitis virus strain A59 small membrane protein E. J. Virol. 74 2333-42 PubMed GONUTS page
