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CRYGA:B3FTL1

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Species (Taxon ID) Cryptococcus gattii (Filobasidiella gattii) (Cryptococcusbacillisporus). (552467)
Gene Name(s) TPS1 (ECO:0000313 with EMBL:ACB46525.1)
Protein Name(s) Trehalose 6-P synthase (ECO:0000313 with EMBL:ACB46525.1)
External Links
UniProt B3FTL1
EMBL EU399551
ProteinModelPortal B3FTL1
CAZy GT20
GO GO:0003824
GO:0005992
InterPro IPR001830
Pfam PF00982

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003825

alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity

PMID:19651856[1]

ECO:0000315

F

Figure 2, Table 3. Trehalose production is completely suppressed in tps1 mutants. Additionally the intermediate T6P is found in the wt but not in the tps1 mutants. Mutants of the second gene in the biosynthetic pathway tps2 have accumulated T6P levels indicating that the previous tps1 step is creating T6P.

complete
CACAO 2054

enables

GO:0003825

alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity

PMID:19651856[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001830

F

Seeded From UniProt

complete

involved_in

GO:0005992

trehalose biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001830

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ngamskulrungroj, P et al. (2009) The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii. Infect. Immun. 77 4584-96 PubMed GONUTS page