CLOAB:ADHE

Species (Taxon ID)	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG5710 / VKM B-1787). (272562)
Gene Name(s)	adhE (synonyms: aad)
Protein Name(s)	Aldehyde-alcohol dehydrogenase Alcohol dehydrogenase ADH Acetaldehyde dehydrogenase [acetylating] ACDH
External Links
UniProt	P33744
EMBL	X72831 L14817 AE001438
PIR	A49346
RefSeq	NP_149325.1 WP_010890846.1
ProteinModelPortal	P33744
STRING	272562.CA_P0162
EnsemblBacteria	AAK76907
GeneID	1116167
KEGG	cac:CA_P0162
PATRIC	32034210
eggNOG	COG1012
HOGENOM	HOG000025256
KO	K04072
OMA	VELNEPF
OrthoDB	EOG6TFCQS
BioCyc	CACE272562:GJIH-4007-MONOMER MetaCyc:AADCLOS-MONOMER
Proteomes	UP000000814
GO	GO:0008774 GO:0004022 GO:0046872 GO:0006066 GO:0015976
Gene3D	3.40.309.10 3.40.605.10
InterPro	IPR001670 IPR018211 IPR016161 IPR016163 IPR016162 IPR015590 IPR012079
Pfam	PF00171 PF00465
PIRSF	PIRSF000111
SUPFAM	SSF53720
PROSITE	PS00913

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004022	alcohol dehydrogenase (NAD) activity	PMID:18726959	ECO:0000314			F		Figure 2 shows that overexpression of the alcohol/aldehyde dehydrogenase gene increased the production of butanol and ethanol.	complete CACAO 4827
enables	GO:0004022	alcohol dehydrogenase (NAD) activity	PMID:18726959	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004022	alcohol dehydrogenase (NAD) activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012079 InterPro:IPR034789	F		Seeded From UniProt	complete
involved_in	GO:0006066	alcohol metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012079	P		Seeded From UniProt	complete
enables	GO:0008774	acetaldehyde dehydrogenase (acetylating) activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012079	F		Seeded From UniProt	complete
involved_in	GO:0015976	carbon utilization	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012079	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001670 InterPro:IPR015590 InterPro:IPR016161 InterPro:IPR016162 InterPro:IPR016163 InterPro:IPR018211	F		Seeded From UniProt	complete
enables	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016163	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001670 InterPro:IPR018211	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001670 InterPro:IPR012079 InterPro:IPR015590 InterPro:IPR016161 InterPro:IPR016162 InterPro:IPR016163 InterPro:IPR018211	P		Seeded From UniProt	complete
enables	GO:0043878	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.2.1.3	F		Seeded From UniProt	complete
enables	GO:0004022	alcohol dehydrogenase (NAD) activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.1.1.1	F		Seeded From UniProt	complete
enables	GO:0004029	aldehyde dehydrogenase (NAD) activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.2.1.3	F		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	P		Seeded From UniProt	complete
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References

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