CHICK:VAMP7

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	VAMP7 (ECO:0000250 with UniProtKB:P51809) (synonyms: SYBL1 (ECO:0000250 with UniProtKB:P51809))
Protein Name(s)	Vesicle-associated membrane protein 7 Synaptobrevin-like protein 1
External Links
UniProt	Q5ZL74
EMBL	AJ719860
RefSeq	NP_001026292.1
UniGene	Gga.50742
ProteinModelPortal	Q5ZL74
SMR	Q5ZL74
STRING	9031.ENSGALP00000012071
PaxDb	Q5ZL74
Ensembl	ENSGALT00000032338
GeneID	422297
KEGG	gga:422297
CTD	6845
eggNOG	COG5143
GeneTree	ENSGT00510000047733
HOGENOM	HOG000042711
HOVERGEN	HBG006675
InParanoid	Q5ZL74
KO	K08515
OMA	CHDRIIY
PhylomeDB	Q5ZL74
NextBio	20824947
PRO	PR:Q5ZL74
Proteomes	UP000000539
GO	GO:0045177 GO:0030054 GO:0009986 GO:0005789 GO:0070062 GO:0005794 GO:0016021 GO:0031902 GO:0005765 GO:0043005 GO:0048471 GO:0045335 GO:0030670 GO:0031201 GO:0045202 GO:0030658 GO:0017156 GO:0008333 GO:0043308 GO:0006888 GO:0043001 GO:0043312 GO:0006911 GO:1900483 GO:0035493 GO:0006906 GO:0016192
Gene3D	3.30.450.50
InterPro	IPR011012 IPR010908 IPR001388
Pfam	PF13774 PF00957
PRINTS	PR00219
SUPFAM	SSF64356
PROSITE	PS50859 PS00417 PS50892

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0045335	phagocytic vesicle	PMID:15470500^[1]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P70280	C	Seeded From UniProt	complete
involved_in	GO:0043312	neutrophil degranulation	PMID:14993220^[2]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P	Seeded From UniProt	complete
involved_in	GO:0043308	eosinophil degranulation	PMID:14993220^[2]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P70280	C	Seeded From UniProt	complete
part_of	GO:0031902	late endosome membrane	PMID:10459012^[3]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	C	Seeded From UniProt	complete
part_of	GO:0031201	SNARE complex	PMID:15133481^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	C	Seeded From UniProt	complete
involved_in	GO:0017156	calcium ion regulated exocytosis	PMID:14993220^[2]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P	Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	PMID:10888671^[5]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P51809	P	Seeded From UniProt	complete
involved_in	GO:0008333	endosome to lysosome transport	PMID:10888671^[5]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P51809	P	Seeded From UniProt	complete
involved_in	GO:0006911	phagocytosis, engulfment	PMID:15133481^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P	Seeded From UniProt	complete
involved_in	GO:0006906	vesicle fusion	PMID:10888671^[5]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P51809	P	Seeded From UniProt	complete
involved_in	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	PMID:16495485^[6]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P	Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	PMID:16495485^[6]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	C	Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	PMID:10459012^[3]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	C	Seeded From UniProt	complete
part_of	GO:0031201	SNARE complex	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0266186 PANTHER:PTN000473885 RGD:621558 SGD:S000004083 TAIR:locus:2080340 UniProtKB:P51809 dictyBase:DDB_G0284951	C	Seeded From UniProt	complete
involved_in	GO:0008333	endosome to lysosome transport	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001079719 RGD:621558 UniProtKB:P51809	P	Seeded From UniProt	complete
involved_in	GO:0006906	vesicle fusion	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000473885 RGD:621558 SGD:S000004083 UniProtKB:P51809 dictyBase:DDB_G0284951	P	Seeded From UniProt	complete
involved_in	GO:0006887	exocytosis	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000473885 RGD:621558	P	Seeded From UniProt	complete
enables	GO:0005484	SNAP receptor activity	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0266186 PANTHER:PTN000473885 RGD:621558 SGD:S000004083	F	Seeded From UniProt	complete
enables	GO:0000149	SNARE binding	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0266186 PANTHER:PTN000473885	F	Seeded From UniProt	complete
involved_in	GO:1903595	positive regulation of histamine secretion by mast cell	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	P	Seeded From UniProt	complete
involved_in	GO:0043320	natural killer cell degranulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	P	Seeded From UniProt	complete
involved_in	GO:0043312	neutrophil degranulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	P	Seeded From UniProt	complete
involved_in	GO:0043308	eosinophil degranulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	P	Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0035577	azurophil granule membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0031201	SNARE complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0031143	pseudopodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0031091	platelet alpha granule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0030667	secretory granule membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0030141	secretory granule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0030027	lamellipodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
involved_in	GO:0008333	endosome to lysosome transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	P	Seeded From UniProt	complete
involved_in	GO:0006906	vesicle fusion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0005802	trans-Golgi network	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51809 ensembl:ENSP00000262640	C	Seeded From UniProt	complete
involved_in	GO:1900483	regulation of protein targeting to vacuolar membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	P	Seeded From UniProt	complete
involved_in	GO:0050775	positive regulation of dendrite morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	P	Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
part_of	GO:0045335	phagocytic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
part_of	GO:0045177	apical part of cell	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
involved_in	GO:0043001	Golgi to plasma membrane protein transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	P	Seeded From UniProt	complete
involved_in	GO:0035493	SNARE complex assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	P	Seeded From UniProt	complete
part_of	GO:0031143	pseudopodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
part_of	GO:0030133	transport vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
part_of	GO:0030027	lamellipodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001388	C	Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001388	P	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0333 UniProtKB-SubCell:SL-0132	C	Seeded From UniProt	complete
part_of	GO:0005764	lysosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0458	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0771 UniProtKB-SubCell:SL-0261	C	Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0256	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C	Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770	C	Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C	Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653	P	Seeded From UniProt	complete
part_of	GO:0030670	phagocytic vesicle membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0205	C	Seeded From UniProt	complete
part_of	GO:0030658	transport vesicle membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0245	C	Seeded From UniProt	complete
part_of	GO:0031902	late endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0151	C	Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0097	C	Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0157	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Braun, V et al. (2004) TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J. 23 4166-76 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Rao, SK et al. (2004) Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J. Biol. Chem. 279 20471-9 PubMed GONUTS page
↑ ^3.0 ^3.1 Advani, RJ et al. (1999) VAMP-7 mediates vesicular transport from endosomes to lysosomes. J. Cell Biol. 146 765-76 PubMed GONUTS page
↑ ^4.0 ^4.1 Pryor, PR et al. (2004) Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep. 5 590-5 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Ward, DM et al. (2000) Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. Mol. Biol. Cell 11 2327-33 PubMed GONUTS page
↑ ^6.0 ^6.1 Siddiqi, SA et al. (2006) Vesicle-associated membrane protein 7 is expressed in intestinal ER. J. Cell. Sci. 119 943-50 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15470500-1] Braun, V et al. (2004) TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J. 23 4166-76 PubMed GONUTS page

[PMID:14993220-2] 2.0 ^2.1 ^2.2 Rao, SK et al. (2004) Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J. Biol. Chem. 279 20471-9 PubMed GONUTS page

[PMID:10459012-3] 3.0 ^3.1 Advani, RJ et al. (1999) VAMP-7 mediates vesicular transport from endosomes to lysosomes. J. Cell Biol. 146 765-76 PubMed GONUTS page

[PMID:15133481-4] 4.0 ^4.1 Pryor, PR et al. (2004) Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep. 5 590-5 PubMed GONUTS page

[PMID:10888671-5] 5.0 ^5.1 ^5.2 Ward, DM et al. (2000) Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. Mol. Biol. Cell 11 2327-33 PubMed GONUTS page

[PMID:16495485-6] 6.0 ^6.1 Siddiqi, SA et al. (2006) Vesicle-associated membrane protein 7 is expressed in intestinal ER. J. Cell. Sci. 119 943-50 PubMed GONUTS page

[PMID:21873635-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:VAMP7

Contents

Annotations

Notes

References

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