CHICK:UBP28

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	USP28
Protein Name(s)	Ubiquitin carboxyl-terminal hydrolase 28 Deubiquitinating enzyme 28 Ubiquitin thioesterase 28 Ubiquitin-specific-processing protease 28
External Links
UniProt	Q5ZID5
EMBL	AJ720849
RefSeq	NP_001026667.1
UniGene	Gga.22397
ProteinModelPortal	Q5ZID5
STRING	9031.ENSGALP00000011273
MEROPS	C19.054
PaxDb	Q5ZID5
GeneID	428246
KEGG	gga:428246
CTD	57646
eggNOG	COG5077
HOGENOM	HOG000007956
HOVERGEN	HBG056030
InParanoid	Q5ZID5
KO	K11849
PhylomeDB	Q5ZID5
NextBio	20829288
PRO	PR:Q5ZID5
Proteomes	UP000000539
GO	GO:0005654 GO:0004221 GO:0004843 GO:0008283 GO:0000077 GO:0006281 GO:0042771 GO:0016579 GO:0010212 GO:0006511
InterPro	IPR001394 IPR009060 IPR018200 IPR028889
Pfam	PF00443
SUPFAM	SSF46934
PROSITE	PS00972 PS00973 PS50235

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0031647	regulation of protein stability	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	P		Seeded From UniProt	complete
involved_in	GO:0007265	Ras protein signal transduction	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	P		Seeded From UniProt	complete
involved_in	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	P		Seeded From UniProt	complete
involved_in	GO:0016579	protein deubiquitination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	P		Seeded From UniProt	complete
involved_in	GO:0010212	response to ionizing radiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	C		Seeded From UniProt	complete
enables	GO:0004843	thiol-dependent ubiquitin-specific protease activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	F		Seeded From UniProt	complete
enables	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	F		Seeded From UniProt	complete
involved_in	GO:0000077	DNA damage checkpoint	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96RU2	P		Seeded From UniProt	complete
involved_in	GO:0031647	regulation of protein stability		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002363832 RGD:1306915 UniProtKB:Q96RU2	P		Seeded From UniProt	complete
involved_in	GO:0016579	protein deubiquitination		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0005632 FB:FBgn0016756 FB:FBgn0260936 MGI:MGI:107698 MGI:MGI:107699 MGI:MGI:1270128 MGI:MGI:1916977 MGI:MGI:1919594 MGI:MGI:1924050 MGI:MGI:2182061 MGI:MGI:3051498 MGI:MGI:3643640 PANTHER:PTN002541993 RGD:1306915 SGD:S000000953 SGD:S000001418 SGD:S000002280 SGD:S000004920 SGD:S000005130 SGD:S000005650 TAIR:locus:2083440 TAIR:locus:2121959 UniProtKB:A0A0B4KI06 UniProtKB:O75317 UniProtKB:O94782 UniProtKB:P45974 UniProtKB:P62068 UniProtKB:Q14694 UniProtKB:Q6R6M4 UniProtKB:Q70CQ2 UniProtKB:Q86T82 UniProtKB:Q8NB14 UniProtKB:Q93008 UniProtKB:Q93009 UniProtKB:Q96RU2 UniProtKB:Q9BXU7 UniProtKB:Q9FPS9 UniProtKB:Q9H9J4 UniProtKB:Q9P275 UniProtKB:Q9P2H5 UniProtKB:Q9UHP3 WB:WBGene00010406 dictyBase:DDB_G0275021	P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002363832 SGD:S000004920 UniProtKB:Q84WU2 UniProtKB:Q93009 UniProtKB:Q9FPT1 UniProtKB:Q9UHP3 UniProtKB:Q9UMW8	C		Seeded From UniProt	complete
enables	GO:0004843	thiol-dependent ubiquitin-specific protease activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0005632 FB:FBgn0016756 FB:FBgn0030366 FB:FBgn0260936 MGI:MGI:107698 MGI:MGI:107699 MGI:MGI:1924050 MGI:MGI:2182061 MGI:MGI:3051372 MGI:MGI:3051498 MGI:MGI:3643640 PANTHER:PTN002541993 PomBase:SPBP8B7.21 RGD:1306915 SGD:S000000163 SGD:S000000262 SGD:S000000953 SGD:S000001418 SGD:S000001806 SGD:S000002280 SGD:S000004920 SGD:S000005130 SGD:S000005650 TAIR:locus:2010622 TAIR:locus:2083440 TAIR:locus:2140074 UniProtKB:O75317 UniProtKB:O94782 UniProtKB:P45974 UniProtKB:P62068 UniProtKB:Q0WX57 UniProtKB:Q14694 UniProtKB:Q6QN14 UniProtKB:Q6R6M4 UniProtKB:Q70CQ2 UniProtKB:Q84WU2 UniProtKB:Q86T82 UniProtKB:Q8LAM0 UniProtKB:Q8NB14 UniProtKB:Q92995 UniProtKB:Q93009 UniProtKB:Q96K76 UniProtKB:Q96RU2 UniProtKB:Q96V54 UniProtKB:Q9FPS0 UniProtKB:Q9FPS9 UniProtKB:Q9FPT1 UniProtKB:Q9H9J4 UniProtKB:Q9P275 UniProtKB:Q9P2H5 UniProtKB:Q9UHP3 WB:WBGene00010406 WB:WBGene00011216	F		Seeded From UniProt	complete
enables	GO:0004197	cysteine-type endopeptidase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2182061 PANTHER:PTN002541993 UniProtKB:O75317 UniProtKB:Q14694 UniProtKB:Q70CQ2 UniProtKB:Q86T82 UniProtKB:Q92995 UniProtKB:Q93009	F		Seeded From UniProt	complete
involved_in	GO:0000077	DNA damage checkpoint		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000607884 UniProtKB:Q96RU2	P		Seeded From UniProt	complete
involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018200	P		Seeded From UniProt	complete
involved_in	GO:0016579	protein deubiquitination	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001394	P		Seeded From UniProt	complete
enables	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001394 InterPro:IPR018200	F		Seeded From UniProt	complete
enables	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.4.19.12	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C		Seeded From UniProt	complete
enables	GO:0008234	cysteine-type peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0788	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0190	C		Seeded From UniProt	complete
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References

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