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CHICK:SPB10

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) SERPINB10 (synonyms: MENT)
Protein Name(s) Heterochromatin-associated protein MENT

Myeloid and erythroid nuclear termination stage-specific protein Serpin B10

External Links
UniProt O73790
EMBL AF053401
RefSeq NP_990228.1
UniGene Gga.415
PDB 2DUT
2H4P
2H4Q
2H4R
PDBsum 2DUT
2H4P
2H4Q
2H4R
ProteinModelPortal O73790
SMR O73790
STRING 9031.ENSGALP00000020960
MEROPS I04.033
PaxDb O73790
Ensembl ENSGALT00000020990
GeneID 395715
KEGG gga:395715
CTD 5273
eggNOG COG4826
GeneTree ENSGT00760000118789
HOGENOM HOG000238519
HOVERGEN HBG005957
InParanoid O73790
KO K13963
OMA KRELSMF
OrthoDB EOG7327PB
PhylomeDB O73790
TreeFam TF352619
EvolutionaryTrace O73790
NextBio 20815785
PRO PR:O73790
Proteomes UP000000539
GO GO:0005694
GO:0005615
GO:0005634
GO:0003677
GO:0004867
GO:0016568
GO:0030261
GO:0010951
GO:0030162
InterPro IPR023796
IPR000215
PANTHER PTHR11461
Pfam PF00079
SMART SM00093
SUPFAM SSF56574

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0031490

chromatin DNA binding

PMID:1729133[1]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(CL:0000562)

Seeded From UniProt

complete

involved_in

GO:0043362

nucleate erythrocyte maturation

PMID:1729133[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030261

chromosome condensation

PMID:1729133[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000562)

Seeded From UniProt

complete

part_of

GO:0000790

nuclear chromatin

PMID:1729133[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000562)

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:8500553[2]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:0000775)
  • part_of:(CL:0000562)

Seeded From UniProt

complete

involved_in

GO:0030261

chromosome condensation

PMID:8500553[2]

ECO:0000314

direct assay evidence used in manual assertion

P

part_of:(GO:0043131)

Seeded From UniProt

complete

involved_in

GO:0010951

negative regulation of endopeptidase activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0028988
FB:FBgn0265137
PANTHER:PTN000156123
RGD:3249
UniProtKB:P05121
UniProtKB:P29508
UniProtKB:P35237
UniProtKB:P50452
UniProtKB:P50453
UniProtKB:Q9UIV8

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002930
FB:FBgn0015586
FB:FBgn0028986
FB:FBgn0031973
FB:FBgn0262057
FB:FBgn0265137
MGI:MGI:108080
MGI:MGI:1915304
MGI:MGI:87963
MGI:MGI:88278
MGI:MGI:894696
PANTHER:PTN000156123
RGD:1306692
RGD:1307404
RGD:2069
RGD:3249
RGD:3326
RGD:3747
RGD:3748
RGD:619833
RGD:631369
RGD:735225
UniProtKB:P01008
UniProtKB:P01009
UniProtKB:P01011
UniProtKB:P01019
UniProtKB:P05121
UniProtKB:P05154
UniProtKB:P08697
UniProtKB:P50453
UniProtKB:Q90935
UniProtKB:Q99574
UniProtKB:Q9TTE1

C

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002930
FB:FBgn0028983
FB:FBgn0028988
FB:FBgn0028990
FB:FBgn0265137
MGI:MGI:101780
MGI:MGI:106603
MGI:MGI:1277952
MGI:MGI:2445361
MGI:MGI:2683293
MGI:MGI:891970
MGI:MGI:894696
MGI:MGI:97608
PANTHER:PTN000156123
RGD:1306692
RGD:1307404
RGD:3249
RGD:3326
RGD:3748
RGD:619817
RGD:619896
RGD:619897
UniProtKB:P01009
UniProtKB:P01012
UniProtKB:P05121
UniProtKB:P05154
UniProtKB:P05155
UniProtKB:P07093
UniProtKB:P08697
UniProtKB:P35237
UniProtKB:P48594
UniProtKB:P50452
UniProtKB:P50453
UniProtKB:Q3ZEJ6
UniProtKB:Q86WD7
UniProtKB:Q90935
UniProtKB:Q96P63
UniProtKB:Q99574
UniProtKB:Q9TTE1
UniProtKB:Q9UIV8
WB:WBGene00005643

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000215

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0030261

chromosome condensation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0226

P

Seeded From UniProt

complete

enables

GO:0030414

peptidase inhibitor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0646

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0010466

negative regulation of peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0646

P

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

involved_in

GO:0006325

chromatin organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0156

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Grigoryev, SA et al. (1992) A novel nonhistone protein (MENT) promotes nuclear collapse at the terminal stage of avian erythropoiesis. Exp. Cell Res. 198 268-75 PubMed GONUTS page
  2. 2.0 2.1 Grigoryev, SA & Woodcock, CL (1993) Stage-specific expression and localization of MENT, a nuclear protein associated with chromatin condensation in terminally differentiating avian erythroid cells. Exp. Cell Res. 206 335-43 PubMed GONUTS page
  3. 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page