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CHICK:SOX8

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) SOX8
Protein Name(s) Transcription factor SOX-8
External Links
UniProt P57074
EMBL AF228664
RefSeq NP_990062.1
UniGene Gga.4309
ProteinModelPortal P57074
SMR P57074
STRING 9031.ENSGALP00000008435
PaxDb P57074
GeneID 395483
KEGG gga:395483
CTD 30812
eggNOG NOG324597
HOGENOM HOG000108876
HOVERGEN HBG002061
InParanoid P57074
KO K09270
PhylomeDB P57074
NextBio 20815563
PRO PR:P57074
Proteomes UP000000539
GO GO:0005634
GO:0003677
GO:0003170
GO:0048709
GO:0006355
GO:0006351
Gene3D 1.10.30.10
InterPro IPR009071
IPR022151
Pfam PF00505
PF12444
SMART SM00398
SUPFAM SSF47095
PROSITE PS50118

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0048709

oligodendrocyte differentiation

PMID:11483257[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0003170

heart valve development

PMID:12351187[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048709

oligodendrocyte differentiation

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98358
MGI:MGI:98370
MGI:MGI:98371
PANTHER:PTN001615967
UniProtKB:P57074

P

Seeded From UniProt

complete

involved_in

GO:0048484

enteric nervous system development

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98370
PANTHER:PTN000030495

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98358
MGI:MGI:98370
MGI:MGI:98371
PANTHER:PTN000741645
RGD:620474
UniProtKB:O18896
UniProtKB:P48436
UniProtKB:P57073

P

Seeded From UniProt

complete

involved_in

GO:0007422

peripheral nervous system development

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98370
PANTHER:PTN000030495

P

Seeded From UniProt

complete

involved_in

GO:0007417

central nervous system development

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98371
PANTHER:PTN001615967

P

Seeded From UniProt

complete

involved_in

GO:0002009

morphogenesis of an epithelium

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000741645
UniProtKB:P48434

P

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98371
PANTHER:PTN000741645

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR031265

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR031265

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Cheng, YC et al. (2001) Sox8 gene expression identifies immature glial cells in developing cerebellum and cerebellar tumours. Brain Res. Mol. Brain Res. 92 193-200 PubMed GONUTS page
  2. Montero, JA et al. (2002) Expression of Sox8, Sox9 and Sox10 in the developing valves and autonomic nerves of the embryonic heart. Mech. Dev. 118 199-202 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page