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CHICK:SKI

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) SKI
Protein Name(s) Ski oncogene

Proto-oncogene c-Ski

External Links
UniProt P49140
EMBL M28517
PIR A32575
B32575
RefSeq NP_001034407.1
UniGene Gga.26111
ProteinModelPortal P49140
SMR P49140
BioGrid 687293
IntAct P49140
PaxDb P49140
GeneID 428181
KEGG gga:428181
CTD 6497
eggNOG NOG82850
HOVERGEN HBG006599
InParanoid P49140
PhylomeDB P49140
NextBio 20829237
PRO PR:P49140
Proteomes UP000000539
GO GO:0005634
GO:0030512
GO:0006351
Gene3D 3.10.260.20
3.10.390.10
InterPro IPR014890
IPR009061
IPR010919
IPR028760
IPR003380
IPR023216
PANTHER PTHR10005
PTHR10005:SF15
Pfam PF08782
PF02437
SMART SM01046
SUPFAM SSF46955
SSF63763

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0043565

sequence-specific DNA binding

PMID:9927733[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:9927733[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005667

transcription factor complex

PMID:9927733[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:9927733[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:F1P0N0

F

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:9927733[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q05951

F

Seeded From UniProt

complete

enables

GO:0070491

repressing transcription factor binding

PMID:9927733[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:9927733[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0019904

protein domain specific binding

PMID:9927733[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P12755

P

Seeded From UniProt

complete

involved_in

GO:0048666

neuron development

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0085450
PANTHER:PTN000000299

P

Seeded From UniProt

complete

enables

GO:0046332

SMAD binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:3645984
PANTHER:PTN000000299
UniProtKB:P12755
UniProtKB:P12757
UniProtKB:P84550
UniProtKB:Q2VWA4

F

Seeded From UniProt

complete

involved_in

GO:0045596

negative regulation of cell differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:106203
PANTHER:PTN000000299

P

Seeded From UniProt

complete

involved_in

GO:0030514

negative regulation of BMP signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0039932
MGI:MGI:3645984
MGI:MGI:98310
PANTHER:PTN000000299
UniProtKB:P12755
UniProtKB:P84550

P

Seeded From UniProt

complete

involved_in

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0085450
MGI:MGI:106203
MGI:MGI:3645984
MGI:MGI:98310
PANTHER:PTN000000299
UniProtKB:P12755
UniProtKB:P12757
UniProtKB:Q2VWA4

P

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028760

P

Seeded From UniProt

complete

enables

GO:0046332

SMAD binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014890

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Cohen, SB et al. (1999) Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents. Nucleic Acids Res. 27 1006-14 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page