CHICK:RBPMS

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	RBPMS (synonyms: HERMES)
Protein Name(s)	RNA-binding protein with multiple splicing RBP-MS Heart and RRM expressed sequence Hermes
External Links
UniProt	Q9W6I1
EMBL	AF129933
RefSeq	NP_990200.1
UniGene	Gga.2695
ProteinModelPortal	Q9W6I1
STRING	9031.ENSGALP00000039532
Ensembl	ENSGALT00000040332
GeneID	395678
KEGG	gga:395678
CTD	348093
eggNOG	NOG255204
GeneTree	ENSGT00500000044861
HOGENOM	HOG000017369
HOVERGEN	HBG069897
InParanoid	Q9W6I1
OMA	QQGWKSR
PhylomeDB	Q9W6I1
NextBio	20815750
PRO	PR:Q9W6I1
Proteomes	UP000000539
GO	GO:0005737 GO:0005634 GO:0000166 GO:0008143 GO:0003713 GO:0010862 GO:0060391 GO:0006355 GO:0006351
Gene3D	3.30.70.330
InterPro	IPR012677 IPR000504
Pfam	PF00076
SMART	SM00360
PROSITE	PS50102

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q6ZRY4	C	Seeded From UniProt	complete
enables	GO:0003729	mRNA binding	PMID:22683258^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0030514	negative regulation of BMP signaling pathway	PMID:22683258^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0048661	positive regulation of smooth muscle cell proliferation	PMID:22683258^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051151	negative regulation of smooth muscle cell differentiation	PMID:22683258^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0048557	embryonic digestive tract morphogenesis	PMID:22683258^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0048565	digestive tract development	PMID:25064856^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0048661	positive regulation of smooth muscle cell proliferation	PMID:25064856^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0030514	negative regulation of BMP signaling pathway	PMID:25064856^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:25064856^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9W6I1	F	Seeded From UniProt	complete
involved_in	GO:0051151	negative regulation of smooth muscle cell differentiation	PMID:25064856^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0060391	positive regulation of SMAD protein signal transduction	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q93062	P	Seeded From UniProt	complete
involved_in	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q93062	P	Seeded From UniProt	complete
enables	GO:0008143	poly(A) binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q93062	F	Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q93062	F	Seeded From UniProt	complete
enables	GO:0035614	snRNA stem-loop binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003449 PANTHER:PTN000827569	F	Seeded From UniProt	complete
involved_in	GO:0000398	mRNA splicing, via spliceosome	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000827569 SGD:S000000323 SGD:S000001448 UniProtKB:P08579	P	Seeded From UniProt	complete
involved_in	GO:1903508	positive regulation of nucleic acid-templated transcription	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0003713	P	Seeded From UniProt	complete
involved_in	GO:0051151	negative regulation of smooth muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q6ZRY4 ensembl:ENSP00000300069	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q6ZRY4 ensembl:ENSP00000300069	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q6ZRY4 ensembl:ENSP00000300069	C	Seeded From UniProt	complete
enables	GO:0003729	mRNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q6ZRY4 ensembl:ENSP00000300069	F	Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000504 InterPro:IPR035979	F	Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR034787	F	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR034787	F	Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Notarnicola, C et al. (2012) The RNA-binding protein RBPMS2 regulates development of gastrointestinal smooth muscle. Gastroenterology 143 687-697.e9 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Sagnol, S et al. (2014) Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity. Nucleic Acids Res. 42 10173-84 PubMed GONUTS page
↑ ^3.0 ^3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:22683258-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Notarnicola, C et al. (2012) The RNA-binding protein RBPMS2 regulates development of gastrointestinal smooth muscle. Gastroenterology 143 687-697.e9 PubMed GONUTS page

[PMID:25064856-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Sagnol, S et al. (2014) Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity. Nucleic Acids Res. 42 10173-84 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:RBPMS

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