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CHICK:Q9I9C5

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) irx1 (ECO:0000313 with EMBL:CAB89806.1)
Protein Name(s) Iroquois homologue-1 (ECO:0000313 with EMBL:CAB89806.1)
External Links
UniProt Q9I9C5
EMBL AJ238354
RefSeq NP_001025509.1
UniGene Gga.2699
ProteinModelPortal Q9I9C5
STRING 9031.ENSGALP00000036186
PaxDb Q9I9C5
GeneID 374185
KEGG gga:374185
CTD 79192
eggNOG NOG279452
HOGENOM HOG000234546
HOVERGEN HBG006180
PhylomeDB Q9I9C5
NextBio 20813690
GO GO:0005634
GO:0043565
GO:0006355
Gene3D 1.10.10.60
InterPro IPR017970
IPR001356
IPR008422
IPR009057
IPR003893
IPR006311
Pfam PF05920
SMART SM00389
SM00548
SUPFAM SSF46689
PROSITE PS00027
PS50071
PS51318

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0001756

somitogenesis

PMID:25372603[1]

ECO:0000315

P

Figure 4: exctopic expression of IRX-1 in the tailbud leads to loss of somites during axial elongation. Shown by whole mount in situ hybridization in rumpless mutant Chick embryos.

complete
CACAO 12929

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001356
InterPro:IPR003893
InterPro:IPR008422
InterPro:IPR009057

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003893

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003893
InterPro:IPR008422
InterPro:IPR017970

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0371

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000401037

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000401037

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Freese, NH et al. (2014) A novel gain-of-function mutation of the proneural IRX1 and IRX2 genes disrupts axis elongation in the Araucana rumpless chicken. PLoS ONE 9 e112364 PubMed GONUTS page