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CHICK:Q9DGI1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CXCR4 (ECO:0000313 with EMBL:AAG09054.1)
Protein Name(s) Chemokine receptor CXCR4 (ECO:0000313 with EMBL:AAG09054.1)
External Links
UniProt Q9DGI1
EMBL AF294794
RefSeq NP_989948.2
UniGene Gga.2305
ProteinModelPortal Q9DGI1
STRING 9031.ENSGALP00000020157
PaxDb Q9DGI1
GeneID 395324
KEGG gga:395324
CTD 7852
eggNOG NOG328039
HOGENOM HOG000234122
HOVERGEN HBG106917
KO K04189
PhylomeDB Q9DGI1
Reactome REACT_253620
REACT_255087
NextBio 20815409
ExpressionAtlas Q9DGI1
GO GO:0031252
GO:0005911
GO:0016023
GO:0005769
GO:0009897
GO:0070062
GO:0030426
GO:0016021
GO:0005770
GO:0005764
GO:0016494
GO:0001667
GO:0007420
GO:0019722
GO:0007281
GO:0008354
GO:0008045
GO:0043217
GO:0061351
GO:0001764
GO:0042119
GO:0001569
GO:0048714
GO:0030334
GO:0050920
GO:0001666
GO:0042098
InterPro IPR001277
IPR022726
IPR000355
IPR000276
IPR017452
PANTHER PTHR24227
PTHR24227:SF7
Pfam PF00001
PF12109
PRINTS PR00657
PR00645
PR00237
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1990869

cellular response to chemokine

PMID:20503359[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • results_in_development_of:(UBERON:0014783)
  • happens_during:(GO:0048568)
  • has_start_location:(UBERON:0002103)
  • has_end_location:(UBERON:0014783)
  • regulates_o_results_in_movement_of:(CL:0000680)

Seeded From UniProt

complete

involved_in

GO:0007154

cell communication

PMID:20503359[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • results_in_development_of:(UBERON:0014783)
  • happens_during:(GO:0048568)
  • has_start_location:(UBERON:0002103)
  • has_end_location:(UBERON:0014783)
  • regulates_o_results_in_movement_of:(CL:0000680)

Seeded From UniProt

complete

involved_in

GO:0014812

muscle cell migration

PMID:20503359[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • results_in_development_of:(UBERON:0014783)
  • happens_during:(GO:0048568)
  • has_start_location:(UBERON:0002103)
  • has_end_location:(UBERON:0014783)
  • regulates_o_results_in_movement_of:(CL:0000680)

Seeded From UniProt

complete

involved_in

GO:1901863

positive regulation of muscle tissue development

PMID:20503359[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • results_in_development_of:(UBERON:0014783)
  • happens_during:(GO:0048568)

Seeded From UniProt

complete

involved_in

GO:0071345

cellular response to cytokine stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

P

Seeded From UniProt

complete

involved_in

GO:0050920

regulation of chemotaxis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

P

Seeded From UniProt

complete

enables

GO:0043130

ubiquitin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

F

Seeded From UniProt

complete

involved_in

GO:0038160

CXCL12-activated CXCR4 signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

P

Seeded From UniProt

complete

enables

GO:0038147

C-X-C motif chemokine 12 receptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

F

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

C

Seeded From UniProt

complete

enables

GO:0032027

myosin light chain binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

F

Seeded From UniProt

complete

enables

GO:0031625

ubiquitin protein ligase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

F

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

C

Seeded From UniProt

complete

part_of

GO:0031252

cell leading edge

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

C

Seeded From UniProt

complete

involved_in

GO:0030155

regulation of cell adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

P

Seeded From UniProt

complete

enables

GO:0019957

C-C chemokine binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

F

Seeded From UniProt

complete

involved_in

GO:0019722

calcium-mediated signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

C

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

C

Seeded From UniProt

complete

part_of

GO:0005770

late endosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

C

Seeded From UniProt

complete

part_of

GO:0005769

early endosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

C

Seeded From UniProt

complete

part_of

GO:0005764

lysosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

C

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

F

Seeded From UniProt

complete

involved_in

GO:0001666

response to hypoxia

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61073
ensembl:ENSP00000386884

P

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276

F

Seeded From UniProt

complete

enables

GO:0004950

chemokine receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000355

F

Seeded From UniProt

complete

involved_in

GO:0006935

chemotaxis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000355

P

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276
InterPro:IPR000355

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276
InterPro:IPR000355
InterPro:IPR001277
InterPro:IPR017452

C

Seeded From UniProt

complete

enables

GO:0019955

cytokine binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022726

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0297

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0297

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Rehimi, R et al. (2010) A novel role of CXCR4 and SDF-1 during migration of cloacal muscle precursors. Dev. Dyn. 239 1622-31 PubMed GONUTS page