CHICK:Q92071

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	ITGB3 (ECO:0000313 with Ensembl:ENSGALP00000000518)
Protein Name(s)	Integrin beta (ECO:0000256 with RuleBase:RU000633)
External Links
UniProt	Q92071
EMBL	AADN03008614 X72378
PIR	S43534
RefSeq	NP_989646.1
UniGene	Gga.1039
SMR	Q92071
Ensembl	ENSGALT00000000519
GeneID	374209
KEGG	gga:374209
CTD	3690
GeneTree	ENSGT00760000119064
HOGENOM	HOG000252936
HOVERGEN	HBG006190
KO	K06493
OMA	GHGQCSC
OrthoDB	EOG7T7GSB
PhylomeDB	Q92071
TreeFam	TF105392
Reactome	REACT_197897 REACT_198056 REACT_198079 REACT_198094 REACT_240643 REACT_250039 REACT_257604 REACT_262058
NextBio	20813713
PRO	PR:Q92071
Proteomes	UP000000539
GO	GO:0071133 GO:0016324 GO:0009897 GO:0008305 GO:0042802 GO:0005178 GO:0004872 GO:0060055 GO:0007160 GO:0007044 GO:0007229 GO:0070527 GO:0030335 GO:0033690 GO:0030334
Gene3D	1.20.5.630 3.40.50.410
InterPro	IPR013111 IPR027068 IPR015812 IPR014836 IPR002369 IPR012896 IPR016201 IPR002035
PANTHER	PTHR10082 PTHR10082:SF25
Pfam	PF07974 PF08725 PF07965 PF00362
PIRSF	PIRSF002512
PRINTS	PR01186
SMART	SM00187 SM00423 SM00327
SUPFAM	SSF103575 SSF53300 SSF69687
PROSITE	PS00243

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0042802	identical protein binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P05106	F	Seeded From UniProt	complete
involved_in	GO:0030334	regulation of cell migration	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O54890	P	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O54890	C	Seeded From UniProt	complete
involved_in	GO:0007044	cell-substrate junction assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O54890	P	Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O54890	F	Seeded From UniProt	complete
contributes_to	GO:0070051	fibrinogen binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000008768 UniProtKB:M0RCF3	F	Seeded From UniProt	complete
involved_in	GO:0033627	cell adhesion mediated by integrin	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004657 MGI:MGI:96615 PANTHER:PTN000801545 UniProtKB:P05106 UniProtKB:P05556 UniProtKB:P18564	P	Seeded From UniProt	complete
involved_in	GO:0016477	cell migration	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96610 PANTHER:PTN000801545	P	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96610 MGI:MGI:96611 MGI:MGI:96612 PANTHER:PTN000801545 RGD:1305581 RGD:2927 UniProtKB:M0RCF3 UniProtKB:P05106 UniProtKB:P05107 UniProtKB:P05556 UniProtKB:P16144 UniProtKB:P18084 UniProtKB:P26010 UniProtKB:P26012 WB:WBGene00003930	C	Seeded From UniProt	complete
part_of	GO:0008305	integrin complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004657 FB:FBgn0010395 MGI:MGI:96613 PANTHER:PTN000801545 RGD:2927 UniProtKB:M0RCF3 UniProtKB:P05106 WB:WBGene00003930 ZFIN:ZDB-GENE-071207-2	C	Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004657 MGI:MGI:96611 MGI:MGI:96614 PANTHER:PTN000801545 UniProtKB:P05107 UniProtKB:P05556 UniProtKB:P18084 UniProtKB:P26010 UniProtKB:P53714	P	Seeded From UniProt	complete
involved_in	GO:0007160	cell-matrix adhesion	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96610 MGI:MGI:96612 PANTHER:PTN000801545 UniProtKB:P05106 UniProtKB:P05107 UniProtKB:P05556 UniProtKB:P16144 UniProtKB:P18084 UniProtKB:P26010 UniProtKB:P26012	P	Seeded From UniProt	complete
part_of	GO:0005925	focal adhesion	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004657 MGI:MGI:96614 PANTHER:PTN000801545 RGD:2927 UniProtKB:M0RCF3 UniProtKB:P05106 UniProtKB:P05556 UniProtKB:P07228 UniProtKB:P18564	C	Seeded From UniProt	complete
enables	GO:0005178	integrin binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96610 MGI:MGI:96612 MGI:MGI:96614 MGI:MGI:96615 PANTHER:PTN000801545 RGD:2927 UniProtKB:P05106	F	Seeded From UniProt	complete
enables	GO:0001968	fibronectin binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000008768 UniProtKB:P05106	F	Seeded From UniProt	complete
involved_in	GO:2000406	positive regulation of T cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:1903053	regulation of extracellular matrix organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
part_of	GO:0099699	integral component of synaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	C	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	C	Seeded From UniProt	complete
part_of	GO:0071133	alpha9-beta1 integrin-ADAM8 complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	C	Seeded From UniProt	complete
involved_in	GO:0061097	regulation of protein tyrosine kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0048146	positive regulation of fibroblast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0048008	platelet-derived growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0043277	apoptotic cell clearance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0036120	cellular response to platelet-derived growth factor stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
part_of	GO:0035866	alphav-beta3 integrin-PKCalpha complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	C	Seeded From UniProt	complete
involved_in	GO:0033690	positive regulation of osteoblast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0032956	regulation of actin cytoskeleton organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0030334	regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	F	Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	C	Seeded From UniProt	complete
involved_in	GO:0010763	positive regulation of fibroblast migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	C	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	C	Seeded From UniProt	complete
involved_in	GO:0007160	cell-matrix adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
involved_in	GO:0007044	cell-substrate junction assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	F	Seeded From UniProt	complete
enables	GO:0005080	protein kinase C binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	F	Seeded From UniProt	complete
involved_in	GO:0001954	positive regulation of cell-matrix adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O54890 ensembl:ENSMUSP00000021028	P	Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027068	F	Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027068	P	Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027068	P	Seeded From UniProt	complete
part_of	GO:0008305	integrin complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027068	C	Seeded From UniProt	complete
involved_in	GO:0070527	platelet aggregation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027068	P	Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P	Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0401	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:Q92071

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