CHICK:Q90Z42

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	ROBO1 (ECO:0000313 with EMBL:AAK94293.1)
Protein Name(s)	Roundabout1 protein (ECO:0000313 with EMBL:AAK94293.1)
External Links
UniProt	Q90Z42
EMBL	AF364047
UniGene	Gga.11034 Gga.51491
ProteinModelPortal	Q90Z42
STRING	9031.ENSGALP00000024963
MEROPS	I43.001
PaxDb	Q90Z42
eggNOG	NOG238978
HOGENOM	HOG000200125
HOVERGEN	HBG085465
PhylomeDB	Q90Z42
GO	GO:0048839 GO:0060173
Gene3D	2.60.40.10
InterPro	IPR007110 IPR013783 IPR013098 IPR003598
Pfam	PF07679
SMART	SM00408
PROSITE	PS50835

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0070100	negative regulation of chemokine-mediated signaling pathway	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
involved_in	GO:0050925	negative regulation of negative chemotaxis	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
involved_in	GO:0050772	positive regulation of axonogenesis	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	F		Seeded From UniProt	complete
involved_in	GO:0035385	Roundabout signaling pathway	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
involved_in	GO:0035025	positive regulation of Rho protein signal transduction	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
involved_in	GO:0030336	negative regulation of cell migration	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
enables	GO:0030275	LRR domain binding	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	F		Seeded From UniProt	complete
involved_in	GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	C		Seeded From UniProt	complete
involved_in	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
involved_in	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	C		Seeded From UniProt	complete
involved_in	GO:0002042	cell migration involved in sprouting angiogenesis	PMID:11472852^[1]	ECO:0000247	sequence alignment evidence used in manual assertion	UniProtKB:Q9Y6N7	P		Seeded From UniProt	complete
part_of	GO:0005623	cell	PMID:26188027^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000023) part_of:(UBERON:0001305)\|part_of:(CL:0000501) part_of:(UBERON:0001305)	Seeded From UniProt	complete
involved_in	GO:0060173	limb development	PMID:11472852^[1]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048839	inner ear development	PMID:18213576^[3]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032986	P		Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032986	P		Seeded From UniProt	complete
involved_in	GO:0035385	Roundabout signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032986	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 Vargesson, N et al. (2001) Expression patterns of Slit and Robo family members during vertebrate limb development. Mech. Dev. 106 175-80 PubMed GONUTS page
↑ Qin, N et al. (2015) New insights into implication of the SLIT/ROBO pathway in the prehierarchical follicle development of hen ovary. Poult. Sci. 94 2235-46 PubMed GONUTS page
↑ Battisti, AC & Fekete, DM (2008) Slits and Robos in the developing chicken inner ear. Dev. Dyn. 237 476-84 PubMed GONUTS page

[PMID:11472852-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 Vargesson, N et al. (2001) Expression patterns of Slit and Robo family members during vertebrate limb development. Mech. Dev. 106 175-80 PubMed GONUTS page

[PMID:26188027-2] Qin, N et al. (2015) New insights into implication of the SLIT/ROBO pathway in the prehierarchical follicle development of hen ovary. Poult. Sci. 94 2235-46 PubMed GONUTS page

[PMID:18213576-3] Battisti, AC & Fekete, DM (2008) Slits and Robos in the developing chicken inner ear. Dev. Dyn. 237 476-84 PubMed GONUTS page

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CHICK:Q90Z42

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