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CHICK:Q90998
Contents
Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
Gene Name(s) | TGFBR3 (ECO:0000313 with Ensembl:ENSGALP00000032713) | |
Protein Name(s) | Transforming growth factor-beta type III receptor (ECO:0000313 with EMBL:AAA49090.1)
Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000032713) | |
External Links | ||
UniProt | Q90998 | |
EMBL | AADN03005659 L01121 | |
PIR | I50428 | |
RefSeq | NP_989670.1 | |
UniGene | Gga.804 | |
IntAct | Q90998 | |
STRING | 9031.ENSGALP00000032713 | |
Ensembl | ENSGALT00000033354 | |
GeneID | 374251 | |
KEGG | gga:374251 | |
CTD | 7049 | |
eggNOG | NOG40778 | |
GeneTree | ENSGT00530000063861 | |
HOGENOM | HOG000090193 | |
HOVERGEN | HBG057515 | |
KO | K05843 | |
OMA | FAIQTCF | |
OrthoDB | EOG72ZCDK | |
PhylomeDB | Q90998 | |
TreeFam | TF337375 | |
NextBio | 20813743 | |
PRO | PR:Q90998 | |
Proteomes | UP000000539 | |
GO | GO:0005783 GO:0009897 GO:0005615 GO:0070062 GO:0034673 GO:0005887 GO:0015026 GO:0005539 GO:0050431 GO:0070123 GO:0001568 GO:0060317 GO:0060038 GO:0016477 GO:0060318 GO:0009790 GO:0048566 GO:0048568 GO:0042118 GO:0001837 GO:0001654 GO:0007507 GO:0003007 GO:0060347 GO:0006955 GO:0035556 GO:0001822 GO:0001889 GO:0030324 GO:0048762 GO:0007162 GO:0022408 GO:0010633 GO:0050680 GO:0010719 GO:0007399 GO:0060021 GO:0060389 GO:0030335 GO:0010628 GO:0032354 GO:0034699 GO:0034695 GO:0007179 GO:0055010 | |
InterPro | IPR001507 IPR017977 | |
Pfam | PF00100 | |
PRINTS | PR00023 | |
SMART | SM00241 | |
PROSITE | PS00682 PS51034 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0070123 |
transforming growth factor beta receptor activity, type III |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0048185 |
activin binding |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043393 |
regulation of protein binding |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0043235 |
receptor complex |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0031100 |
animal organ regeneration |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030512 |
negative regulation of transforming growth factor beta receptor signaling pathway |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030511 |
positive regulation of transforming growth factor beta receptor signaling pathway |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0017134 |
fibroblast growth factor binding |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016049 |
cell growth |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0008201 |
heparin binding |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007181 |
transforming growth factor beta receptor complex assembly |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0065003 |
protein-containing complex assembly |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005615 |
extracellular space |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0031012 |
extracellular matrix |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005160 |
transforming growth factor beta receptor binding |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001666 |
response to hypoxia |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0070123 |
transforming growth factor beta receptor activity, type III |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
contributes_to |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007507 |
heart development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007507 |
heart development |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048762 |
mesenchymal cell differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048568 |
embryonic organ development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048566 |
embryonic digestive tract development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042118 |
endothelial cell activation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030335 |
positive regulation of cell migration |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030324 |
lung development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030324 |
lung development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0022408 |
negative regulation of cell-cell adhesion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
NOT|involved_in |
GO:0010468 |
regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
NOT|involved_in |
GO:0010468 |
regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
NOT|involved_in |
GO:0010468 |
regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048568 |
embryonic organ development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007399 |
nervous system development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001889 |
liver development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001837 |
epithelial to mesenchymal transition |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001822 |
kidney development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001654 |
eye development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0070123 |
transforming growth factor beta receptor activity, type III |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0060317 |
cardiac epithelial to mesenchymal transition |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016477 |
cell migration |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005539 |
glycosaminoglycan binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0003007 |
heart morphogenesis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001837 |
epithelial to mesenchymal transition |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0070123 |
transforming growth factor beta receptor activity, type III |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060389 |
pathway-restricted SMAD protein phosphorylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060317 |
cardiac epithelial to mesenchymal transition |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051271 |
negative regulation of cellular component movement |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0050431 |
transforming growth factor beta binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0046332 |
SMAD binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0043235 |
receptor complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035556 |
intracellular signal transduction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034699 |
response to luteinizing hormone |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034695 |
response to prostaglandin E |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0034673 |
inhibin-betaglycan-ActRII complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032354 |
response to follicle-stimulating hormone |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0015026 |
coreceptor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0009897 |
external side of plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006955 |
immune response |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005114 |
type II transforming growth factor beta receptor binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0005024 |
transforming growth factor beta-activated receptor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001837 |
epithelial to mesenchymal transition |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q03167 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0060317 |
cardiac epithelial to mesenchymal transition |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048762 |
mesenchymal cell differentiation |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016477 |
cell migration |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007162 |
negative regulation of cell adhesion |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 1.29 1.30 1.31 1.32 1.33 1.34 1.35 1.36 Barnett, JV et al. (1994) Cloning and developmental expression of the chick type II and type III TGF beta receptors. Dev. Dyn. 199 12-27 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 Brown, CB et al. (1999) Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart. Science 283 2080-2 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Olivey, HE et al. (2003) Expression of the type III TGFbeta receptor during chick organogenesis. Anat Rec A Discov Mol Cell Evol Biol 272 383-7 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Boyer, AS & Runyan, RB (2001) TGFbeta Type III and TGFbeta Type II receptors have distinct activities during epithelial-mesenchymal cell transformation in the embryonic heart. Dev. Dyn. 221 454-9 PubMed GONUTS page
- ↑ 5.0 5.1 Mercado-Pimentel, ME & Runyan, RB (2007) Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart. Cells Tissues Organs (Print) 185 146-56 PubMed GONUTS page
- ↑ 6.0 6.1 Lai, YT et al. (2000) Activin receptor-like kinase 2 can mediate atrioventricular cushion transformation. Dev. Biol. 222 1-11 PubMed GONUTS page
c
e
- GO:0048566 ! embryonic digestive tract development
- GO:0048568 ! embryonic organ development
- GO:0042118 ! endothelial cell activation
- GO:0001837 ! epithelial to mesenchymal transition
- Eukaryota
- Euteleostomi
- GO:0009897 ! external side of plasma membrane
- GO:0005615 ! extracellular space
- GO:0031012 ! extracellular matrix
- GO:0005576 ! extracellular region
- GO:0001654 ! eye development
i
n
o
p
r
t
- Testudines + Archosauria group
- Theropoda
- GO:0005024 ! transforming growth factor beta receptor activity
- GO:0007181 ! transforming growth factor beta receptor complex assembly
- GO:0005160 ! transforming growth factor beta receptor binding
- GO:0007179 ! transforming growth factor beta receptor signaling pathway
- GO:0070123 ! transforming growth factor beta receptor activity, type III
- GO:0050431 ! transforming growth factor beta binding
- GO:0005114 ! type II transforming growth factor beta receptor binding