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CHICK:Q90978

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) HGF/SF (ECO:0000313 with EMBL:CAA58864.1)
Protein Name(s) Hepatocyte growth factor /scatter factor (ECO:0000313 with EMBL:CAA58864.1)
External Links
UniProt Q90978
EMBL X84045
PIR I51285
RefSeq NP_001025541.2
UniGene Gga.28385
ProteinModelPortal Q90978
SMR Q90978
MEROPS S01.976
GeneID 395941
KEGG gga:395941
CTD 3082
HOGENOM HOG000112892
HOVERGEN HBG004381
KO K05460
PhylomeDB Q90978
NextBio 20816006
GO GO:0004252
Gene3D 2.40.20.10
InterPro IPR024174
IPR000001
IPR013806
IPR018056
IPR003014
IPR003609
IPR001254
IPR001314
IPR009003
Pfam PF00051
PF00024
PF00089
PIRSF PIRSF001152
PRINTS PR00722
SMART SM00130
SM00473
SM00020
SUPFAM SSF50494
SSF57440
PROSITE PS00021
PS50070
PS50948
PS50240

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1902725

negative regulation of satellite cell differentiation

PMID:10825239[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000594)

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:10825239[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1902724

positive regulation of skeletal muscle satellite cell proliferation

PMID:10825239[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000594)

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

PMID:10825239[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000594)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:12064460[2]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

PMID:12064460[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000594)

Seeded From UniProt

complete

involved_in

GO:1902724

positive regulation of skeletal muscle satellite cell proliferation

PMID:12064460[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:12064460[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000594)

Seeded From UniProt

complete

involved_in

GO:0001934

positive regulation of protein phosphorylation

PMID:12064460[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000594)

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

enables

GO:0004252

serine-type endopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001254
InterPro:IPR001314

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001254
InterPro:IPR001314

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Leshem, Y et al. (2000) Hepatocyte growth factor (HGF) inhibits skeletal muscle cell differentiation: a role for the bHLH protein twist and the cdk inhibitor p27. J. Cell. Physiol. 184 101-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Leshem, Y & Halevy, O (2002) Phosphorylation of pRb is required for HGF-induced muscle cell proliferation and is p27kip1-dependent. J. Cell. Physiol. 191 173-82 PubMed GONUTS page