CHICK:Q8QG94

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	SUFU (ECO:0000313 with Ensembl:ENSGALP00000013127)
Protein Name(s)	Suppressor of fused homolog (ECO:0000256 with PIRNR:PIRNR011844)
External Links
UniProt	Q8QG94
EMBL	AADN03004970 AF487888
RefSeq	NP_989595.1
UniGene	Gga.2771
SMR	Q8QG94
STRING	9031.ENSGALP00000032551
Ensembl	ENSGALT00000013142
GeneID	374118
KEGG	gga:374118
CTD	51684
eggNOG	NOG72477
GeneTree	ENSGT00390000009747
HOGENOM	HOG000007864
HOVERGEN	HBG061539
KO	K06229
OMA	GDTAITF
OrthoDB	EOG7RV9FV
PhylomeDB	Q8QG94
Reactome	REACT_269353 REACT_269806 REACT_270296 REACT_270602
NextBio	20813634
Proteomes	UP000000539
GO	GO:0005737 GO:0005634 GO:0072372 GO:0042802 GO:0042994 GO:0001947 GO:2000059 GO:1901621 GO:0000122 GO:0001843 GO:0043588 GO:0021776 GO:0021775
InterPro	IPR020941 IPR024314 IPR007768 IPR016591
PANTHER	PTHR10928
Pfam	PF05076 PF12470
PIRSF	PIRSF011844

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0005737	cytoplasm	PMID:10433824^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:10433824^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0043433	negative regulation of DNA-binding transcription factor activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0005355 PANTHER:PTN000859153	P	Seeded From UniProt	complete
involved_in	GO:0042994	cytoplasmic sequestering of transcription factor	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1345643 PANTHER:PTN000859153	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0005355 PANTHER:PTN000859153 UniProtKB:Q9UMX1	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0005355 MGI:MGI:1345643 PANTHER:PTN000859153 UniProtKB:Q8QG94 UniProtKB:Q9UMX1	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1345643 PANTHER:PTN000859153 UniProtKB:Q8QG94 UniProtKB:Q9UMX1	C	Seeded From UniProt	complete
involved_in	GO:0045879	negative regulation of smoothened signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UMX1 ensembl:ENSP00000358918	P	Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UMX1 ensembl:ENSP00000358918	F	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UMX1 ensembl:ENSP00000358918	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UMX1 ensembl:ENSP00000358918	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UMX1 ensembl:ENSP00000358918	C	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UMX1 ensembl:ENSP00000358918	P	Seeded From UniProt	complete
involved_in	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0060976	coronary vasculature development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0045879	negative regulation of smoothened signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0043588	skin development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0042994	cytoplasmic sequestering of transcription factor	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0035904	aorta development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0021513	spinal cord dorsal/ventral patterning	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
enables	GO:0008013	beta-catenin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	F	Seeded From UniProt	complete
involved_in	GO:0007368	determination of left/right symmetry	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
part_of	GO:0005929	cilium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	C	Seeded From UniProt	complete
involved_in	GO:0003281	ventricular septum development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0001947	heart looping	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0001843	neural tube closure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Z0P7 ensembl:ENSMUSP00000107498	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016591	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Pearse, RV 2nd et al. (1999) Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators. Dev. Biol. 212 323-36 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10433824-1] 1.0 ^1.1 Pearse, RV 2nd et al. (1999) Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators. Dev. Biol. 212 323-36 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:Q8QG94

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