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CHICK:Q788Q8

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) bFGF (ECO:0000313 with EMBL:CAA40139.1)
Protein Name(s) Fibroblast growth factor (ECO:0000256 with RuleBase:RU049442)

FGF (ECO:0000256 with RuleBase:RU049442)

External Links
UniProt Q788Q8
EMBL X56804
UniGene Gga.39646
ProteinModelPortal Q788Q8
ExpressionAtlas Q788Q8
GO GO:0005829
GO:0005615
GO:0005634
GO:0000186
GO:0001525
GO:0060128
GO:0008543
GO:0010001
GO:0030324
GO:0008285
GO:0001759
GO:0045766
GO:0090263
GO:0021940
GO:0010595
GO:0001938
GO:0070374
GO:0045669
GO:0051897
GO:0045944
GO:0051726
GO:0046668
GO:0048678
GO:0048864
GO:0021762
GO:0060129
InterPro IPR008996
IPR028223
IPR002209
PANTHER PTHR11486
PTHR11486:SF68
PRINTS PR00263
SUPFAM SSF50353

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0072248

metanephric glomerular visceral epithelial cell differentiation

PMID:8200474[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0072089

stem cell proliferation

PMID:16916506[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0002346)

Seeded From UniProt

complete

involved_in

GO:0070660

inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration

PMID:8789806[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060563

neuroepithelial cell differentiation

PMID:16916506[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

PMID:16916506[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0002346)

Seeded From UniProt

complete

involved_in

GO:0045766

positive regulation of angiogenesis

PMID:7601314[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042060

wound healing

PMID:8789806[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

occurs_in:(UBERON:0000970)

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

PMID:8789806[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

occurs_in:(UBERON:0010312)

Seeded From UniProt

complete

involved_in

GO:0022008

neurogenesis

PMID:16916506[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010756

positive regulation of plasminogen activation

PMID:7601314[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0008283

cell population proliferation

PMID:3186711[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

part_of:(GO:0030326)

Seeded From UniProt

complete

involved_in

GO:0008283

cell population proliferation

PMID:8789806[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

occurs_in:(UBERON:0010312)

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

PMID:1647988[6]

ECO:0000353

physical interaction evidence used in manual assertion

CHEBI:28304

F

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

PMID:3186711[5]

ECO:0000353

physical interaction evidence used in manual assertion

CHEBI:28304

F

part_of:(GO:0030326)

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

PMID:7601314[4]

ECO:0000353

physical interaction evidence used in manual assertion

CHEBI:28304

F

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

PMID:16916506[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:1647988[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:2022692[7]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000187)

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:7748784[8]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0004341)
  • part_of:(UBERON:0002532)

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:8200474[1]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0000080)
  • part_of:(UBERON:0004347)

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:8789806[3]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0000045)
  • part_of:(CL:0000561)
  • part_of:(UBERON:0001795)
  • part_of:(UBERON:0001790)

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

PMID:8789806[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0013731)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:7748784[8]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0000089)
  • part_of:(UBERON:0000090)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:8200474[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000653)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:8789806[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0013731)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:16916506[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:7748784[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0002089

lens morphogenesis in camera-type eye

PMID:8789806[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001894

tissue homeostasis

PMID:8789806[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

occurs_in:(UBERON:0000970)

Seeded From UniProt

complete

involved_in

GO:0001707

mesoderm formation

PMID:1647988[6]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

enables

GO:0005104

fibroblast growth factor receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028223

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028223

C

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002209

F

Seeded From UniProt

complete

involved_in

GO:0008543

fibroblast growth factor receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028223

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Dono, R & Zeller, R (1994) Cell-type-specific nuclear translocation of fibroblast growth factor-2 isoforms during chicken kidney and limb morphogenesis. Dev. Biol. 163 316-30 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Martín, C et al. (2006) FGF2 plays a key role in embryonic cerebrospinal fluid trophic properties over chick embryo neuroepithelial stem cells. Dev. Biol. 297 402-16 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 Lee, KH & Cotanche, DA (1996) Potential role of bFGF and retinoic acid in the regeneration of chicken cochlear hair cells. Hear. Res. 94 1-13 PubMed GONUTS page
  4. 4.0 4.1 4.2 Ribatti, D et al. (1995) Endogenous basic fibroblast growth factor is implicated in the vascularization of the chick embryo chorioallantoic membrane. Dev. Biol. 170 39-49 PubMed GONUTS page
  5. 5.0 5.1 Munaim, SI et al. (1988) Developmental changes in fibroblast growth factor in the chicken embryo limb bud. Proc. Natl. Acad. Sci. U.S.A. 85 8091-3 PubMed GONUTS page
  6. 6.0 6.1 6.2 Parlow, MH et al. (1991) Localization of bFGF-like proteins as punctate inclusions in the preseptation myocardium of the chicken embryo. Dev. Biol. 146 139-47 PubMed GONUTS page
  7. Consigli, SA & Joseph-Silverstein, J (1991) Immunolocalization of basic fibroblast growth factor during chicken cardiac development. J. Cell. Physiol. 146 379-85 PubMed GONUTS page
  8. 8.0 8.1 8.2 Riese, J et al. (1995) Nucleo-cytoplasmic translocation and secretion of fibroblast growth factor-2 during avian gastrulation. Mech. Dev. 49 13-22 PubMed GONUTS page