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CHICK:Q645M5

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) AREG (ECO:0000313 with EMBL:AAU21467.1) (synonyms: AREGB (ECO:0000313 with Ensembl:ENSGALP00000017644))
Protein Name(s) Amphiregulin (ECO:0000313 with EMBL:AAU21467.1)

Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000017644)

External Links
UniProt Q645M5
EMBL AADN03003930
AY725836
RefSeq NP_001026708.1
UniGene Gga.22139
STRING 9031.ENSGALP00000017644
Ensembl ENSGALT00000017665
GeneID 428752
KEGG gga:428752
CTD 428752
eggNOG NOG41450
GeneTree ENSGT00530000063708
HOGENOM HOG000034038
KO K09782
OMA GTPCEME
OrthoDB EOG7XDBH6
TreeFam TF332773
NextBio 20829663
PRO PR:Q645M5
Proteomes UP000000539
GO GO:0009986
GO:0005737
GO:0005615
GO:0005634
GO:0007173
GO:0007186
GO:0045740
GO:0032355
InterPro IPR000742
IPR013032
IPR015497
PANTHER PTHR10740
SMART SM00181
PROSITE PS00022
PS50026

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0008284

positive regulation of cell population proliferation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107508
MGI:MGI:88068
MGI:MGI:96070
MGI:MGI:98724
MGI:MGI:99439
PANTHER:PTN000843338
RGD:2149
RGD:3849
RGD:620299
UniProtKB:O14944
UniProtKB:P15514
UniProtKB:Q6UW88

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919170
MGI:MGI:96070
PANTHER:PTN000843338
RGD:2149
RGD:2526
RGD:620275
RGD:620299
UniProtKB:P01135
UniProtKB:Q6UW88
UniProtKB:Q99075

F

Seeded From UniProt

complete

involved_in

GO:0007173

epidermal growth factor receptor signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107508
MGI:MGI:96070
PANTHER:PTN000843338
RGD:2149
RGD:2526
RGD:620275
UniProtKB:P15514
UniProtKB:Q99075

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107508
MGI:MGI:96070
PANTHER:PTN000843338
RGD:2149
RGD:3849
RGD:620299
UniProtKB:O14944
UniProtKB:P01135
UniProtKB:P15514
UniProtKB:Q99075

C

Seeded From UniProt

complete

enables

GO:0005154

epidermal growth factor receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107508
MGI:MGI:1919170
MGI:MGI:96070
PANTHER:PTN000843338
RGD:2149
RGD:2526
RGD:3849
RGD:620275
UniProtKB:P01135
UniProtKB:Q6UW88

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P15514
ensembl:ENSP00000379097

C

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P15514
ensembl:ENSP00000379097

P

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P15514
ensembl:ENSP00000379097

P

Seeded From UniProt

complete

involved_in

GO:0007173

epidermal growth factor receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P15514
ensembl:ENSP00000379097

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P15514
ensembl:ENSP00000379097

C

Seeded From UniProt

complete

involved_in

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P31955
ensembl:ENSMUSP00000031325

P

Seeded From UniProt

complete

involved_in

GO:0032355

response to estradiol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P31955
ensembl:ENSMUSP00000031325

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P31955
ensembl:ENSMUSP00000031325

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P31955
ensembl:ENSMUSP00000031325

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P31955
ensembl:ENSMUSP00000031325

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page