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CHICK:Q5ILH0

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) HNF4alpha (ECO:0000313 with EMBL:AAW33562.1)
Protein Name(s) Hepatic nuclear factor 4alpha (ECO:0000313 with EMBL:AAW33562.1)
External Links
UniProt Q5ILH0
EMBL AY700581
RefSeq NP_001026026.1
UniGene Gga.19277
ProteinModelPortal Q5ILH0
SMR Q5ILH0
STRING 9031.ENSGALP00000006799
PaxDb Q5ILH0
GeneID 419198
KEGG gga:419198
CTD 3172
eggNOG NOG241134
HOGENOM HOG000260822
HOVERGEN HBG005606
KO K07292
PhylomeDB Q5ILH0
Reactome REACT_230830
REACT_258806
NextBio 20822295
PRO PR:Q5ILH0
ExpressionAtlas Q5ILH0
GO GO:0005737
GO:0005634
GO:0005504
GO:0004879
GO:0000979
GO:0003705
GO:0003707
GO:0008270
GO:0007596
GO:0042593
GO:0006629
GO:0030308
GO:0008285
GO:0006591
GO:0055091
GO:2000189
GO:0045944
GO:0010470
GO:0050796
GO:0019216
GO:0009749
GO:0007548
GO:0023019
GO:0060395
GO:0070328
GO:0006805
Gene3D 1.10.565.10
3.30.50.10
InterPro IPR003068
IPR008946
IPR000536
IPR001723
IPR001628
IPR013088
Pfam PF00104
PF00105
PRINTS PR01282
PR00398
PR00047
SMART SM00430
SM00399
SUPFAM SSF48508
PROSITE PS00031
PS51030

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:1990841

promoter-specific chromatin binding

PMID:24418194[1]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(GO:0005634)

Seeded From UniProt

complete

enables

GO:0001046

core promoter sequence-specific DNA binding

PMID:24418194[1]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(GO:0005634)

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:24418194[1]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(GO:0005634)

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:24418194[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(GO:0005634)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:24418194[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0002107)

Seeded From UniProt

complete

involved_in

GO:0043401

steroid hormone mediated signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003707

P

Seeded From UniProt

complete

involved_in

GO:0003323

type B pancreatic cell development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039067

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR039067

F

Seeded From UniProt

complete

enables

GO:0003707

steroid hormone receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR001723

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR013088

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR013088

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

involved_in

GO:0050796

regulation of insulin secretion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039067

P

Seeded From UniProt

complete

involved_in

GO:0055088

lipid homeostasis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039067

P

Seeded From UniProt

complete

involved_in

GO:0070365

hepatocyte differentiation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039067

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Yang, Q et al. (2014) Transcriptional regulation of chicken cytochrome P450 2D49 basal expression by CCAAT/enhancer-binding protein α and hepatocyte nuclear factor 4α. FEBS J. 281 1379-92 PubMed GONUTS page