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CHICK:Q4U127

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) No Information Provided.
Protein Name(s) Toll-interleukin 1 receptor domain-containing adaptor protein (ECO:0000313 with EMBL:AAY51675.1)

Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000001610)

External Links
UniProt Q4U127
EMBL AADN03008312
DQ019929
RefSeq NP_001020000.1
UniGene Gga.12311
STRING 9031.ENSGALP00000001610
Ensembl ENSGALT00000001612
GeneID 419715
KEGG gga:419715
CTD 114609
eggNOG NOG80263
GeneTree ENSGT00510000048428
HOGENOM HOG000068972
HOVERGEN HBG054203
KO K05403
OMA AELRFMY
OrthoDB EOG7TQV26
PhylomeDB Q4U127
TreeFam TF330734
Reactome REACT_241289
REACT_24954
REACT_25089
REACT_255374
NextBio 20822733
PRO PR:Q4U127
Proteomes UP000000539
GO GO:0005737
GO:0005886
GO:0070935
GO:0007166
GO:0071221
GO:0071223
GO:0050830
GO:0007249
GO:0045087
GO:0002755
GO:0030099
GO:0044130
GO:0070374
GO:0043123
GO:0032738
GO:0045410
GO:0032757
GO:0046330
GO:0051092
GO:0090073
GO:0034137
GO:0034145
GO:0032760
GO:0032496
GO:0035665
GO:0035681
GO:0034134
GO:0034142
GO:0034146
GO:0002224
Gene3D 3.40.50.10140
InterPro IPR000157
IPR017279
PANTHER PTHR22662
Pfam PF13676
PIRSF PIRSF037750
SUPFAM SSF52200
PROSITE PS50104

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0002224

toll-like receptor signaling pathway

PMID:19776194[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0090073

positive regulation of protein homodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0070935

3'-UTR-mediated mRNA stabilization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0070374

positive regulation of ERK1 and ERK2 cascade

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0051092

positive regulation of NF-kappaB transcription factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

F

Seeded From UniProt

complete

involved_in

GO:0046330

positive regulation of JNK cascade

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0045410

positive regulation of interleukin-6 biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

F

Seeded From UniProt

complete

involved_in

GO:0035665

TIRAP-dependent toll-like receptor 4 signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

enables

GO:0035663

Toll-like receptor 2 binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

F

Seeded From UniProt

complete

enables

GO:0035662

Toll-like receptor 4 binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

F

Seeded From UniProt

complete

involved_in

GO:0034145

positive regulation of toll-like receptor 4 signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0034137

positive regulation of toll-like receptor 2 signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0032760

positive regulation of tumor necrosis factor production

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0032757

positive regulation of interleukin-8 production

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0032738

positive regulation of interleukin-15 production

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0032496

response to lipopolysaccharide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

involved_in

GO:0007250

activation of NF-kappaB-inducing kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

C

Seeded From UniProt

complete

enables

GO:0005080

protein kinase C binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P58753
ensembl:ENSP00000376445

F

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000157

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Lu, Y et al. (2009) Expression profiles of genes in Toll-like receptor-mediated signaling of broilers infected with Clostridium perfringens. Clin. Vaccine Immunol. 16 1639-47 PubMed GONUTS page