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CHICK:PSN2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PSEN2
Protein Name(s) Presenilin-2

PS-2 Presenilin-2 NTF subunit Presenilin-2 CTF subunit

External Links
UniProt Q90X07
EMBL AY043493
RefSeq NP_989633.1
UniGene Gga.2719
MEROPS A22.002
PaxDb Q90X07
GeneID 374188
KEGG gga:374188
CTD 5664
eggNOG NOG237920
HOGENOM HOG000240228
HOVERGEN HBG011375
InParanoid Q90X07
KO K04522
NextBio 20813693
PRO PR:Q90X07
Proteomes UP000000539
GO GO:0005789
GO:0000139
GO:0016021
GO:0004190
GO:0035556
GO:0007219
InterPro IPR001493
IPR001108
IPR006639
PANTHER PTHR10202
PTHR10202:SF11
Pfam PF01080
PRINTS PR01072
PR01074
SMART SM00730

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0050435

amyloid-beta metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109284
PANTHER:PTN000024431

P

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000024431
WB:WBGene00004769

C

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109284
PANTHER:PTN000024431

C

Seeded From UniProt

complete

part_of

GO:0030018

Z disc

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109284
PANTHER:PTN000024431

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0019947
PANTHER:PTN000024431

C

Seeded From UniProt

complete

involved_in

GO:0007220

Notch receptor processing

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0019947
PANTHER:PTN000024431

P

Seeded From UniProt

complete

involved_in

GO:0006816

calcium ion transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109284
PANTHER:PTN000024431

P

Seeded From UniProt

complete

involved_in

GO:0006509

membrane protein ectodomain proteolysis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000024431
UniProtKB:P49810

P

Seeded From UniProt

complete

part_of

GO:0005938

cell cortex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0019947
PANTHER:PTN000024431

C

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0019947
PANTHER:PTN000024429
UniProtKB:P49768
UniProtKB:P49810

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1202717
PANTHER:PTN000024429
UniProtKB:P49768

C

Seeded From UniProt

complete

enables

GO:0004175

endopeptidase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0019947
MGI:MGI:109284
MGI:MGI:1202717
PANTHER:PTN000024429
RGD:3425
UniProtKB:P49768

F

Seeded From UniProt

complete

enables

GO:0004190

aspartic-type endopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001108
InterPro:IPR006639

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001493

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001108
InterPro:IPR006639

C

Seeded From UniProt

complete

involved_in

GO:0016485

protein processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001108

P

Seeded From UniProt

complete

involved_in

GO:0035556

intracellular signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001493

P

Seeded From UniProt

complete

enables

GO:0042500

aspartic endopeptidase activity, intramembrane cleaving

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001493

F

Seeded From UniProt

complete

involved_in

GO:0042987

amyloid precursor protein catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001493

P

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0007219

Notch signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0914

P

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page