CHICK:PROX1

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	PROX1
Protein Name(s)	Prospero homeobox protein 1 Homeobox prospero-like protein PROX1 PROX-1
External Links
UniProt	Q91018
EMBL	U46563
PIR	JC5495
RefSeq	NP_001005616.1
UniGene	Gga.2460
ProteinModelPortal	Q91018
SMR	Q91018
STRING	9031.ENSGALP00000015911
PaxDb	Q91018
GeneID	395802
KEGG	gga:395802
CTD	5629
eggNOG	NOG323972
HOGENOM	HOG000115708
HOVERGEN	HBG053693
InParanoid	Q91018
PhylomeDB	Q91018
NextBio	20815870
PRO	PR:Q91018
Proteomes	UP000000539
GO	GO:0005737 GO:0005634 GO:0003677 GO:0055013 GO:0021516 GO:0007507 GO:0070365 GO:0001822 GO:0002088 GO:0070309 GO:0001889 GO:0001945 GO:0001946 GO:0021915 GO:0030910 GO:0043049 GO:0031016 GO:0006355 GO:0060042 GO:0048511 GO:0006351
Gene3D	1.10.10.500
InterPro	IPR023082 IPR009057 IPR007738
PANTHER	PTHR12198
Pfam	PF05044
SUPFAM	SSF46689

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005634	nucleus	PMID:15624319^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0004016)	Seeded From UniProt	complete
part_of	GO:0005623	cell	PMID:23071561^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001846)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21676907^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001790) part_of:(UBERON:0001791)	Seeded From UniProt	complete
involved_in	GO:0070365	hepatocyte differentiation	PMID:15232737^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070309	lens fiber cell morphogenesis	PMID:11850194^[5]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060042	retina morphogenesis in camera-type eye	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0055013	cardiac muscle cell development	PMID:15232737^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043049	otic placode formation	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0031016	pancreas development	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030910	olfactory placode formation	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021915	neural tube development	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021516	dorsal spinal cord development	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:11850194^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:11850194^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0002088	lens development in camera-type eye	PMID:15232737^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002088	lens development in camera-type eye	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001946	lymphangiogenesis	PMID:15232737^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001945	lymph vessel development	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001889	liver development	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001822	kidney development	PMID:11789987^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070309	lens fiber cell morphogenesis	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97772 PANTHER:PTN000258078 UniProtKB:Q91018 UniProtKB:Q92786	P		Seeded From UniProt	complete
involved_in	GO:0060836	lymphatic endothelial cell differentiation	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97772 PANTHER:PTN000258078 UniProtKB:Q92786	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004595 MGI:MGI:97772 PANTHER:PTN000258074	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004595 MGI:MGI:97772 PANTHER:PTN000258074 RGD:1306890 UniProtKB:Q91018 UniProtKB:Q92786	C		Seeded From UniProt	complete
involved_in	GO:0001946	lymphangiogenesis	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000258078 UniProtKB:Q91018 UniProtKB:Q92786	P		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004595 MGI:MGI:97772 PANTHER:PTN000258074 UniProtKB:Q92786	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009057 InterPro:IPR023082 InterPro:IPR037131	F		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007738 InterPro:IPR039350	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037 GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238 UniProtKB-KW:KW-0371	F		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Wilting, J et al. (2003) Lymphangioblasts in embryonic lymphangiogenesis. Lymphat Res Biol 1 33-40 PubMed GONUTS page
↑ Freeman, SD & Daudet, N (2012) Artificial induction of Sox21 regulates sensory cell formation in the embryonic chicken inner ear. PLoS ONE 7 e46387 PubMed GONUTS page
↑ Verra, DM et al. (2011) Early onset and differential temporospatial expression of melanopsin isoforms in the developing chicken retina. Invest. Ophthalmol. Vis. Sci. 52 5111-20 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Dudas, J et al. (2004) The homeobox transcription factor Prox1 is highly conserved in embryonic hepatoblasts and in adult and transformed hepatocytes, but is absent from bile duct epithelium. Anat. Embryol. 208 359-66 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Duncan, MK et al. (2002) Prox1 is differentially localized during lens development. Mech. Dev. 112 195-8 PubMed GONUTS page
↑ ^6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 Rodriguez-Niedenführ, M et al. (2001) Prox1 is a marker of ectodermal placodes, endodermal compartments, lymphatic endothelium and lymphangioblasts. Anat. Embryol. 204 399-406 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15624319-1] Wilting, J et al. (2003) Lymphangioblasts in embryonic lymphangiogenesis. Lymphat Res Biol 1 33-40 PubMed GONUTS page

[PMID:23071561-2] Freeman, SD & Daudet, N (2012) Artificial induction of Sox21 regulates sensory cell formation in the embryonic chicken inner ear. PLoS ONE 7 e46387 PubMed GONUTS page

[PMID:21676907-3] Verra, DM et al. (2011) Early onset and differential temporospatial expression of melanopsin isoforms in the developing chicken retina. Invest. Ophthalmol. Vis. Sci. 52 5111-20 PubMed GONUTS page

[PMID:15232737-4] 4.0 ^4.1 ^4.2 ^4.3 Dudas, J et al. (2004) The homeobox transcription factor Prox1 is highly conserved in embryonic hepatoblasts and in adult and transformed hepatocytes, but is absent from bile duct epithelium. Anat. Embryol. 208 359-66 PubMed GONUTS page

[PMID:11850194-5] 5.0 ^5.1 ^5.2 Duncan, MK et al. (2002) Prox1 is differentially localized during lens development. Mech. Dev. 112 195-8 PubMed GONUTS page

[PMID:11789987-6] 6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 Rodriguez-Niedenführ, M et al. (2001) Prox1 is a marker of ectodermal placodes, endodermal compartments, lymphatic endothelium and lymphangioblasts. Anat. Embryol. 204 399-406 PubMed GONUTS page

[PMID:21873635-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:PROX1

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