CHICK:PRKDC

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	PRKDC (synonyms: XRCC7)
Protein Name(s)	DNA-dependent protein kinase catalytic subunit DNA-PK catalytic subunit DNA-PKcs
External Links
UniProt	Q8QGX4
EMBL	AB016240 AB028136 U83109
RefSeq	NP_989989.1
UniGene	Gga.189
ProteinModelPortal	Q8QGX4
STRING	9031.ENSGALP00000024527
PaxDb	Q8QGX4
PRIDE	Q8QGX4
GeneID	395376
KEGG	gga:395376
CTD	5591
eggNOG	COG5032
HOGENOM	HOG000168371
HOVERGEN	HBG053681
InParanoid	Q8QGX4
KO	K06642
PhylomeDB	Q8QGX4
Reactome	REACT_115694 REACT_115715
NextBio	20815460
PRO	PR:Q8QGX4
Proteomes	UP000000539
GO	GO:0070419 GO:0005730 GO:0005654 GO:0005524 GO:0003677 GO:0004677 GO:0006281 GO:0006302 GO:0000724 GO:0006303 GO:0072431
Gene3D	1.10.1070.11
InterPro	IPR016024 IPR003152 IPR011009 IPR012582 IPR000403 IPR018936 IPR003151 IPR014009
Pfam	PF02259 PF02260 PF08163 PF00454
SMART	SM00146
SUPFAM	SSF48371 SSF56112
PROSITE	PS51189 PS51190 PS00915 PS00916 PS50290

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P78527	P		Seeded From UniProt	complete
part_of	GO:0070419	nonhomologous end joining complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P78527	C		Seeded From UniProt	complete
involved_in	GO:0033152	immunoglobulin V(D)J recombination		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104779 PANTHER:PTN002596777	P		Seeded From UniProt	complete
involved_in	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104779 PANTHER:PTN002476708	P		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001673367 dictyBase:DDB_G0281167	P		Seeded From UniProt	complete
involved_in	GO:0006302	double-strand break repair		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104779 PANTHER:PTN001673367 UniProtKB:P78527	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0045035 FB:FBgn0053554 MGI:MGI:104779 MGI:MGI:1928394 PANTHER:PTN000124197 RGD:1593265 RGD:68371 SGD:S000000340 SGD:S000001141 SGD:S000003827 UniProtKB:P78527 UniProtKB:Q13315 UniProtKB:Q96Q15 UniProtKB:Q9FR53 UniProtKB:Q9Y4A5 WB:WBGene00000226 WB:WBGene00007028	C		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001673367 UniProtKB:P78527	F		Seeded From UniProt	complete
involved_in	GO:0000723	telomere maintenance		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104779 PANTHER:PTN001673367	P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004677	P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004674	P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004674	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012582	F		Seeded From UniProt	complete
enables	GO:0004677	DNA-dependent protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012582 InterPro:IPR037706	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012582	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012582	C		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037706	P		Seeded From UniProt	complete
involved_in	GO:0006303	double-strand break repair via nonhomologous end joining	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012582	P		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018936 InterPro:IPR036940	F		Seeded From UniProt	complete
involved_in	GO:0006303	double-strand break repair via nonhomologous end joining	Reactome:R-GGA-353423	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-GGA-353313 Reactome:R-GGA-353298 Reactome:R-GGA-353283 Reactome:R-GGA-351434	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	Reactome:R-GGA-351433	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0723	F		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
part_of	GO:0005730	nucleolus	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0188	C		Seeded From UniProt	complete
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References

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