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CHICK:PDIA3

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PDIA3 (synonyms: ERP57, GRP58)
Protein Name(s) Protein disulfide-isomerase A3

Endoplasmic reticulum resident protein 57 ER protein 57 ERp57 Glucose-regulated thiol oxidoreductase 58 kDa protein

External Links
UniProt Q8JG64
EMBL AY122886
RefSeq NP_989441.1
UniGene Gga.3802
ProteinModelPortal Q8JG64
SMR Q8JG64
BioGrid 674949
STRING 9031.ENSGALP00000013574
PaxDb Q8JG64
PRIDE Q8JG64
Ensembl ENSGALT00000013589
GeneID 373899
KEGG gga:373899
CTD 2923
eggNOG COG0526
GeneTree ENSGT00760000119201
HOGENOM HOG000162459
HOVERGEN HBG005920
InParanoid Q8JG64
KO K08056
OMA RFAHTNS
OrthoDB EOG7VHSX1
PhylomeDB Q8JG64
TreeFam TF106382
Reactome REACT_197578
REACT_256357
NextBio 20813431
PRO PR:Q8JG64
Proteomes UP000000539
GO GO:0009986
GO:0005783
GO:0005788
GO:0070062
GO:0005634
GO:0044822
GO:0003756
GO:0045454
GO:2001238
GO:0006457
GO:0034976
Gene3D 3.40.30.10
InterPro IPR005788
IPR005792
IPR012336
IPR017937
IPR013766
Pfam PF00085
SUPFAM SSF52833
TIGRFAMs TIGR01130
TIGR01126
PROSITE PS00194
PS51352

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0034976

response to endoplasmic reticulum stress

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000432607
TAIR:locus:2082712
TAIR:locus:2204670
UniProtKB:P07237
UniProtKB:Q9XI01

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95834
PANTHER:PTN001448745
RGD:68430
UniProtKB:P30101

C

Seeded From UniProt

complete

involved_in

GO:0006457

protein folding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000432607
SGD:S000000548
SGD:S000002926
UniProtKB:C0H4Y6

P

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0014002
MGI:MGI:104864
MGI:MGI:95834
MGI:MGI:97464
PANTHER:PTN000432607
RGD:68430
TAIR:locus:2014681
TAIR:locus:2018134
TAIR:locus:2082712
TAIR:locus:2093447
TAIR:locus:2204670
UniProtKB:P07237
UniProtKB:P30101
UniProtKB:Q9FF55
UniProtKB:Q9XI01
WB:WBGene00003963

C

Seeded From UniProt

complete

enables

GO:0003756

protein disulfide isomerase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919080
PANTHER:PTN000432607
RGD:3244
RGD:619835
SGD:S000000548
SGD:S000002926
TAIR:locus:2204670
UniProtKB:C0H4Y6
UniProtKB:O48949
UniProtKB:P07237
UniProtKB:Q4WH99
WB:WBGene00003962
WB:WBGene00003963
WB:WBGene00003964

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0015037

P

Seeded From UniProt

complete

involved_in

GO:2001238

positive regulation of extrinsic apoptotic signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27773
ensembl:ENSMUSP00000028683

P

Seeded From UniProt

complete

involved_in

GO:0098761

cellular response to interleukin-7

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27773
ensembl:ENSMUSP00000028683

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27773
ensembl:ENSMUSP00000028683

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27773
ensembl:ENSMUSP00000028683

C

Seeded From UniProt

complete

part_of

GO:0042824

MHC class I peptide loading complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30101
ensembl:ENSP00000300289

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30101
ensembl:ENSP00000300289

F

Seeded From UniProt

complete

enables

GO:0015037

peptide disulfide oxidoreductase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30101
ensembl:ENSP00000300289

F

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30101
ensembl:ENSP00000300289

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30101
ensembl:ENSP00000300289

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P30101
ensembl:ENSP00000300289

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:V9HVY3
ensembl:ENSP00000300289

C

Seeded From UniProt

complete

enables

GO:0003756

protein disulfide isomerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005792

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005788

F

Seeded From UniProt

complete

involved_in

GO:0045454

cell redox homeostasis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013766
InterPro:IPR017937

P

Seeded From UniProt

complete

enables

GO:0003756

protein disulfide isomerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.3.4.1

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256
UniProtKB-SubCell:SL-0095

C

Seeded From UniProt

complete

part_of

GO:0005788

endoplasmic reticulum lumen

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0096

C

Seeded From UniProt

complete

part_of

GO:0042470

melanosome

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0161

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page