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CHICK:PARP1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PARP1 (synonyms: ADPRT)
Protein Name(s) Poly [ADP-ribose] polymerase 1

PARP-1 ADP-ribosyltransferase diphtheria toxin-like 1 ARTD1 NAD(+) ADP-ribosyltransferase 1 ADPRT 1 Poly[ADP-ribose] synthase 1

External Links
UniProt P26446
EMBL X52690
PIR JH0581
RefSeq NP_990594.1
UniGene Gga.5209
PDB 1A26
1EFY
1PAX
2PAW
2PAX
3PAX
4PAX
PDBsum 1A26
1EFY
1PAX
2PAW
2PAX
3PAX
4PAX
ProteinModelPortal P26446
SMR P26446
STRING 9031.ENSGALP00000038037
PaxDb P26446
PRIDE P26446
GeneID 396199
KEGG gga:396199
CTD 142
eggNOG NOG243963
HOGENOM HOG000030402
HOVERGEN HBG053513
InParanoid P26446
KO K10798
PhylomeDB P26446
EvolutionaryTrace P26446
NextBio 20816251
PRO PR:P26446
Proteomes UP000000539
GO GO:0005634
GO:0003677
GO:0051287
GO:0003950
GO:0008270
GO:0070212
Gene3D 1.20.142.10
2.20.140.10
3.30.1740.10
3.40.50.10190
3.90.228.10
InterPro IPR001357
IPR008288
IPR012982
IPR012317
IPR004102
IPR008893
IPR001510
Pfam PF00533
PF08063
PF00644
PF02877
PF05406
PF00645
PIRSF PIRSF000489
SMART SM00292
SM00773
SUPFAM SSF142921
SSF47587
SSF52113
PROSITE PS50172
PS51060
PS51059
PS00347
PS50064

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1905168

positive regulation of double-strand break repair via homologous recombination

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P09874

P

Seeded From UniProt

complete

involved_in

GO:0030592

DNA ADP-ribosylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P09874

P

Seeded From UniProt

complete

involved_in

GO:0070213

protein auto-ADP-ribosylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P09874

P

Seeded From UniProt

complete

involved_in

GO:0018424

peptidyl-glutamic acid poly-ADP-ribosylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P09874

P

Seeded From UniProt

complete

enables

GO:1990404

protein ADP-ribosylase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P09874

F

Seeded From UniProt

complete

involved_in

GO:0018312

peptidyl-serine ADP-ribosylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P09874

P

Seeded From UniProt

complete

involved_in

GO:1990966

ATP generation from poly-ADP-D-ribose

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P09874

P

Seeded From UniProt

complete

involved_in

GO:0070212

protein poly-ADP-ribosylation

PMID:15674325[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:1990404

protein ADP-ribosylase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1340806
PANTHER:PTN000396992
UniProtKB:P09874
UniProtKB:Q9UGN5

F

Seeded From UniProt

complete

involved_in

GO:0070212

protein poly-ADP-ribosylation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1340806
PANTHER:PTN000396992
RGD:2053
UniProtKB:P09874
UniProtKB:P26446
WB:WBGene00004049
WB:WBGene00004050
dictyBase:DDB_G0278741
dictyBase:DDB_G0292820

P

Seeded From UniProt

complete

involved_in

GO:0006302

double-strand break repair

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1340806
MGI:MGI:1891258
PANTHER:PTN000396992
UniProtKB:P09874
UniProtKB:Q9Y6F1
dictyBase:DDB_G0278741
dictyBase:DDB_G0292820

P

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010247
MGI:MGI:1340806
MGI:MGI:1341112
PANTHER:PTN000396992
UniProtKB:P09874
UniProtKB:Q9UGN5

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1340806
MGI:MGI:1341112
PANTHER:PTN000396992
RGD:2053
TAIR:locus:2005523
UniProtKB:P09874
UniProtKB:Q9UGN5
dictyBase:DDB_G0278741
dictyBase:DDB_G0279195
dictyBase:DDB_G0292820

C

Seeded From UniProt

complete

enables

GO:0003950

NAD+ ADP-ribosyltransferase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010247
MGI:MGI:1340806
MGI:MGI:1341112
PANTHER:PTN000396992
RGD:2053
TAIR:locus:2042511
UniProtKB:P09874
UniProtKB:Q9Y6F1
WB:WBGene00004049
WB:WBGene00004050

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001510
InterPro:IPR008288
InterPro:IPR036957

F

Seeded From UniProt

complete

enables

GO:0003950

NAD+ ADP-ribosyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004102
InterPro:IPR008288
InterPro:IPR012317
InterPro:IPR036616

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008288

C

Seeded From UniProt

complete

involved_in

GO:0006471

protein ADP-ribosylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004102
InterPro:IPR008288
InterPro:IPR036616

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001510
InterPro:IPR008288
InterPro:IPR036957

F

Seeded From UniProt

complete

enables

GO:0051287

NAD binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008288

F

Seeded From UniProt

complete

enables

GO:0003950

NAD+ ADP-ribosyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.4.2.30

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0328

F

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0188

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Yu, M et al. (2005) PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation. Oncogene 24 1982-93 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page