CHICK:PAN2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	PAN2 (ECO:0000255 with HAMAP-Rule:MF_03182) (synonyms: USP52)
Protein Name(s)	PAB-dependent poly(A)-specific ribonuclease subunit PAN2 (ECO:0000255 with HAMAP-Rule:MF_03182) Inactive ubiquitin carboxyl-terminal hydrolase 52 (ECO:0000255 with HAMAP-Rule:MF_03182) PAB1P-dependent poly(A)-nuclease (ECO:0000255 with HAMAP-Rule:MF_03182) PAN deadenylation complex catalytic subunit 2 (ECO:0000255 with HAMAP-Rule:MF_03182)
External Links
UniProt	Q5F450
EMBL	AJ851450
RefSeq	NP_001012972.1
UniGene	Gga.18769
ProteinModelPortal	Q5F450
STRING	9031.ENSGALP00000004379
PaxDb	Q5F450
Ensembl	ENSGALT00000004388 ENSGALT00000044564
GeneID	429172
KEGG	gga:429172
CTD	9924
eggNOG	COG0847
GeneTree	ENSGT00390000013978
HOGENOM	HOG000230585
HOVERGEN	HBG089847
InParanoid	Q5F450
KO	K12571
OMA	EEPHLYM
PhylomeDB	Q5F450
Reactome	REACT_197393
NextBio	20829982
PRO	PR:Q5F450
Proteomes	UP000000539
GO	GO:0000932 GO:0005634 GO:0031251 GO:0000175 GO:0003676 GO:0004535 GO:0006397 GO:0090503
Gene3D	2.130.10.10 3.30.420.10
HAMAP	MF_03182
InterPro	IPR006055 IPR013520 IPR028881 IPR012337 IPR028889 IPR015943 IPR017986
Pfam	PF00929 PF13423
SMART	SM00479
SUPFAM	SSF50978 SSF53098
PROSITE	PS50235

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0031251	PAN complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q504Q3	C		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q504Q3	F		Seeded From UniProt	complete
enables	GO:0000175	3'-5'-exoribonuclease activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q504Q3	F		Seeded From UniProt	complete
part_of	GO:0031251	PAN complex		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000404664 SGD:S000003062 UniProtKB:Q504Q3	C		Seeded From UniProt	complete
contributes_to	GO:0004535	poly(A)-specific ribonuclease activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000404664 SGD:S000003062 UniProtKB:Q504Q3	F		Seeded From UniProt	complete
part_of	GO:0000932	P-body		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1918984 PANTHER:PTN000404664	C		Seeded From UniProt	complete
involved_in	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0033352 PANTHER:PTN000404664 SGD:S000003062	P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004527	P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0000175	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004535	P		Seeded From UniProt	complete
involved_in	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030843	P		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR036397	F		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030843	F		Seeded From UniProt	complete
involved_in	GO:0006397	mRNA processing	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030843	P		Seeded From UniProt	complete
part_of	GO:0031251	PAN complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030843	C		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.13.4	F		Seeded From UniProt	complete
involved_in	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166126	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166126	C		Seeded From UniProt	complete
involved_in	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166126	P		Seeded From UniProt	complete
part_of	GO:0000932	P-body	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166126	C		Seeded From UniProt	complete
part_of	GO:0031251	PAN complex	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166126	C		Seeded From UniProt	complete
enables	GO:0004535	poly(A)-specific ribonuclease activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166126	F		Seeded From UniProt	complete
involved_in	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166126	P		Seeded From UniProt	complete
involved_in	GO:0006397	mRNA processing	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0507	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0004527	exonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0269	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0000932	P-body	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0230	C		Seeded From UniProt	complete
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