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CHICK:PA24A

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PLA2G4A (synonyms: CPLA2, PLA2G4)
Protein Name(s) Cytosolic phospholipase A2

cPLA2 Phospholipase A2 group IVA Phospholipase A2 Phosphatidylcholine 2-acylhydrolase Lysophospholipase

External Links
UniProt P49147
EMBL U10329
PIR I50699
RefSeq NP_990754.1
UniGene Gga.3723
ProteinModelPortal P49147
SMR P49147
STRING 9031.ENSGALP00000038517
PaxDb P49147
Ensembl ENSGALT00000008121
GeneID 396394
KEGG gga:396394
CTD 5321
eggNOG NOG257248
GeneTree ENSGT00550000074489
HOGENOM HOG000115420
HOVERGEN HBG053479
InParanoid P49147
KO K16342
OMA ETLIHNR
OrthoDB EOG73V6JM
PhylomeDB P49147
Reactome REACT_194344
REACT_194362
REACT_197168
REACT_197169
REACT_197170
REACT_197172
REACT_197175
REACT_197176
REACT_197223
REACT_236020
REACT_241087
REACT_253568
NextBio 20816436
PRO PR:P49147
Proteomes UP000000539
GO GO:0016023
GO:0005829
GO:0005783
GO:0005794
GO:0005509
GO:0047498
GO:0005544
GO:0004622
GO:0050482
GO:0071236
GO:0046456
GO:0009395
GO:0042127
Gene3D 2.60.40.150
InterPro IPR016035
IPR000008
IPR002642
Pfam PF00168
PF01735
SMART SM00239
SM00022
SUPFAM SSF49562
SSF52151
PROSITE PS50004
PS51210

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0047498

calcium-dependent phospholipase A2 activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2685493
PANTHER:PTN000842854
RGD:67366
UniProtKB:P0C869
UniProtKB:P47712
UniProtKB:Q86XP0

F

Seeded From UniProt

complete

involved_in

GO:0046475

glycerophospholipid catabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000076790
UniProtKB:P0C869
UniProtKB:Q86XP0
UniProtKB:Q9UP65

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1195256
PANTHER:PTN002582260
RGD:67366
UniProtKB:P47712

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1195256
PANTHER:PTN002582260

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1195256
PANTHER:PTN002582260

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919144
MGI:MGI:1925640
MGI:MGI:2685493
PANTHER:PTN000076790
RGD:67366

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002582260
RGD:67366

C

Seeded From UniProt

complete

enables

GO:0005544

calcium-dependent phospholipid binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000842854
UniProtKB:P47712

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000842854
UniProtKB:P47712

F

Seeded From UniProt

complete

enables

GO:0004623

phospholipase A2 activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1195256
MGI:MGI:1919144
MGI:MGI:1925640
MGI:MGI:2384819
MGI:MGI:2685493
PANTHER:PTN000076790
UniProtKB:A0A1D8PEB1
UniProtKB:P47712

F

Seeded From UniProt

complete

enables

GO:0004620

phospholipase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002642

F

Seeded From UniProt

complete

involved_in

GO:0009395

phospholipid catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002642

P

Seeded From UniProt

complete

enables

GO:0004622

lysophospholipase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.5

F

Seeded From UniProt

complete

enables

GO:0102568

phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.4

F

Seeded From UniProt

complete

enables

GO:0004623

phospholipase A2 activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.4

F

Seeded From UniProt

complete

enables

GO:0102567

phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.4

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0968

C

Seeded From UniProt

complete

involved_in

GO:0016042

lipid catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0442

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page