CHICK:OPTN

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	OPTN
Protein Name(s)	Optineurin Ag9-C5 FIP-2
External Links
UniProt	Q90Z16
EMBL	AF380358 AF389351
RefSeq	NP_989567.1
UniGene	Gga.4189
ProteinModelPortal	Q90Z16
SMR	Q90Z16
STRING	9031.ENSGALP00000022287
PaxDb	Q90Z16
PRIDE	Q90Z16
Ensembl	ENSGALT00000022327
GeneID	374079
KEGG	gga:374079
CTD	10133
eggNOG	NOG138369
GeneTree	ENSGT00530000063808
HOGENOM	HOG000231899
HOVERGEN	HBG106481
InParanoid	Q90Z16
OMA	AHPNLDT
PhylomeDB	Q90Z16
Reactome	REACT_197901
NextBio	20813600
PRO	PR:Q90Z16
Proteomes	UP000000539
GO	GO:0005776 GO:0031410 GO:0048471 GO:0005802 GO:0050829 GO:0090161 GO:0043001 GO:0016236 GO:0001920 GO:0000042
InterPro	IPR021063
Pfam	PF11577

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0005794	Golgi apparatus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96CV9	C	Seeded From UniProt	complete
involved_in	GO:0090161	Golgi ribbon formation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001268349 UniProtKB:Q96CV9	P	Seeded From UniProt	complete
enables	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1338074 MGI:MGI:1918898 PANTHER:PTN001268347	F	Seeded From UniProt	complete
involved_in	GO:0034067	protein localization to Golgi apparatus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001268349 UniProtKB:Q96CV9	P	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001268349 RGD:628886 UniProtKB:Q96CV9	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0041205 MGI:MGI:1338074 PANTHER:PTN001268347 RGD:628886 UniProtKB:Q9Y6K9	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0041205 PANTHER:PTN001268347 RGD:628886 UniProtKB:Q9Y6K9	C	Seeded From UniProt	complete
enables	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8K3K8 ensembl:ENSMUSP00000110648	F	Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8K3K8 ensembl:ENSMUSP00000110648	C	Seeded From UniProt	complete
involved_in	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8K3K8 ensembl:ENSMUSP00000110648	P	Seeded From UniProt	complete
involved_in	GO:0034613	cellular protein localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8K3K8 ensembl:ENSMUSP00000110648	P	Seeded From UniProt	complete
involved_in	GO:1904417	positive regulation of xenophagy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
involved_in	GO:0090161	Golgi ribbon formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
involved_in	GO:0061734	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
involved_in	GO:0050829	defense response to Gram-negative bacterium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
involved_in	GO:0043001	Golgi to plasma membrane protein transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	F	Seeded From UniProt	complete
involved_in	GO:0034620	cellular response to unfolded protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
involved_in	GO:0034067	protein localization to Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
enables	GO:0031593	polyubiquitin modification-dependent protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	F	Seeded From UniProt	complete
enables	GO:0030674	protein binding, bridging	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	F	Seeded From UniProt	complete
enables	GO:0017137	Rab GTPase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	F	Seeded From UniProt	complete
involved_in	GO:0010508	positive regulation of autophagy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	F	Seeded From UniProt	complete
involved_in	GO:0007030	Golgi organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	C	Seeded From UniProt	complete
part_of	GO:0005802	trans-Golgi network	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	C	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	C	Seeded From UniProt	complete
involved_in	GO:0001920	negative regulation of receptor recycling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96CV9 ensembl:ENSP00000368022	P	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032939	C	Seeded From UniProt	complete
involved_in	GO:0006914	autophagy	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032939	P	Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032939	P	Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032939	C	Seeded From UniProt	complete
enables	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032939 InterPro:IPR034735	F	Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C	Seeded From UniProt	complete
involved_in	GO:0006914	autophagy	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0072	P	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0333 UniProtKB-SubCell:SL-0132	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0005776	autophagosome	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0023	C	Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0232	C	Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0198	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:OPTN

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