CHICK:LCK

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	LCK
Protein Name(s)	Proto-oncogene tyrosine-protein kinase LCK Protein-tyrosine kinase C-TKL p56tk1
External Links
UniProt	P42683
EMBL	X60380 M85043 J03579
PIR	A42126
UniGene	Gga.11320
ProteinModelPortal	P42683
SMR	P42683
PRIDE	P42683
HOVERGEN	HBG008761
InParanoid	P42683
PhylomeDB	P42683
BRENDA	2.7.10.2
Proteomes	UP000000539
GO	GO:0045121 GO:0000242 GO:0005886 GO:0005524 GO:0004715 GO:0004722 GO:0004713 GO:0042169 GO:0006919 GO:0006882 GO:0016311 GO:0018108 GO:2001244 GO:0050870 GO:0042493 GO:0030217
Gene3D	3.30.505.10
InterPro	IPR011009 IPR000719 IPR017441 IPR001245 IPR000980 IPR001452 IPR008266 IPR020635
Pfam	PF07714 PF00017 PF00018
PRINTS	PR00401 PR00452 PR00109
SMART	SM00252 SM00326 SM00219
SUPFAM	SSF50044 SSF55550 SSF56112
PROSITE	PS00107 PS50011 PS00109 PS50001 PS50002

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	P		Seeded From UniProt	complete
involved_in	GO:0050870	positive regulation of T cell activation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	C		Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	P		Seeded From UniProt	complete
enables	GO:0042169	SH2 domain binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	F		Seeded From UniProt	complete
involved_in	GO:0030217	T cell differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	P		Seeded From UniProt	complete
involved_in	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	P		Seeded From UniProt	complete
involved_in	GO:0006882	cellular zinc ion homeostasis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	P		Seeded From UniProt	complete
enables	GO:0004722	protein serine/threonine phosphatase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	F		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	F		Seeded From UniProt	complete
part_of	GO:0000242	pericentriolar material	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P06239	C		Seeded From UniProt	complete
involved_in	GO:0050853	B cell receptor signaling pathway		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96756 PANTHER:PTN000700970	P		Seeded From UniProt	complete
involved_in	GO:0038083	peptidyl-tyrosine autophosphorylation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002521528 UniProtKB:Q9H3Y6 WB:WBGene00005077	P		Seeded From UniProt	complete
part_of	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002521528 UniProtKB:P08631	C		Seeded From UniProt	complete
involved_in	GO:0030217	T cell differentiation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000700970 UniProtKB:P06239	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002521528 RGD:621423	P		Seeded From UniProt	complete
involved_in	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002521528 UniProtKB:P07948	P		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0262733 PANTHER:PTN002521528 RGD:2641 RGD:620795 RGD:621017 UniProtKB:P12931	F		Seeded From UniProt	complete
enables	GO:0004715	non-membrane spanning protein tyrosine kinase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95527 PANTHER:PTN002521528 UniProtKB:P09769 UniProtKB:P51451 UniProtKB:Q13882 WB:WBGene00005077	F		Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004722	P		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR008266	F		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020635	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR008266 InterPro:IPR020635	P		Seeded From UniProt	complete
enables	GO:0004715	non-membrane spanning protein tyrosine kinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.10.2	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0829	F		Seeded From UniProt	complete
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References

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