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CHICK:KAP0

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PRKAR1A
Protein Name(s) cAMP-dependent protein kinase type I-alpha regulatory subunit
External Links
UniProt Q5ZM91
EMBL AJ719493
RefSeq NP_001007846.1
UniGene Gga.4713
ProteinModelPortal Q5ZM91
SMR Q5ZM91
STRING 9031.ENSGALP00000006731
PaxDb Q5ZM91
PRIDE Q5ZM91
Ensembl ENSGALT00000034558
GeneID 417438
KEGG gga:417438
CTD 5573
eggNOG COG0664
GeneTree ENSGT00530000062947
HOGENOM HOG000196669
HOVERGEN HBG002025
InParanoid Q5ZM91
KO K04739
OMA SAMAACK
OrthoDB EOG72JWG6
PhylomeDB Q5ZM91
Reactome REACT_197541
REACT_232229
REACT_237504
REACT_242424
REACT_243824
REACT_244857
REACT_269353
NextBio 20820735
PRO PR:Q5ZM91
Proteomes UP000000539
GO GO:0031588
GO:0005952
GO:0031594
GO:0005886
GO:0030552
GO:0004862
GO:0008603
GO:0060038
GO:0001707
GO:2000480
GO:0045214
Gene3D 2.60.120.10
InterPro IPR002373
IPR012198
IPR003117
IPR018490
IPR018488
IPR000595
IPR014710
Pfam PF00027
PF02197
PIRSF PIRSF000548
PRINTS PR00103
SMART SM00100
SM00394
SUPFAM SSF47391
SSF51206
PROSITE PS00888
PS00889
PS50042

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0047555

3',5'-cyclic-GMP phosphodiesterase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000180782
dictyBase:DDB_G0274383

F

Seeded From UniProt

complete

involved_in

GO:0019934

cGMP-mediated signaling

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000180782
dictyBase:DDB_G0274383

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000180782
WB:WBGene00002190
dictyBase:DDB_G0274383

C

Seeded From UniProt

complete

involved_in

GO:2000480

negative regulation of cAMP-dependent protein kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

P

Seeded From UniProt

complete

involved_in

GO:0046007

negative regulation of activated T cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

P

Seeded From UniProt

complete

part_of

GO:0044853

plasma membrane raft

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

C

Seeded From UniProt

complete

enables

GO:0034236

protein kinase A catalytic subunit binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

F

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

C

Seeded From UniProt

complete

enables

GO:0031625

ubiquitin protein ligase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

F

Seeded From UniProt

complete

part_of

GO:0031588

nucleotide-activated protein kinase complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

C

Seeded From UniProt

complete

enables

GO:0019904

protein domain specific binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

F

Seeded From UniProt

complete

enables

GO:0008603

cAMP-dependent protein kinase regulator activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

F

Seeded From UniProt

complete

part_of

GO:0005930

axoneme

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

C

Seeded From UniProt

complete

enables

GO:0004862

cAMP-dependent protein kinase inhibitor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

F

Seeded From UniProt

complete

part_of

GO:0001772

immunological synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P10644
ensembl:ENSP00000376475

C

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

C

Seeded From UniProt

complete

involved_in

GO:0060038

cardiac muscle cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

P

Seeded From UniProt

complete

involved_in

GO:0045214

sarcomere organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

C

Seeded From UniProt

complete

part_of

GO:0031594

neuromuscular junction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

C

Seeded From UniProt

complete

enables

GO:0008603

cAMP-dependent protein kinase regulator activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

F

Seeded From UniProt

complete

involved_in

GO:0007507

heart development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

P

Seeded From UniProt

complete

involved_in

GO:0006469

negative regulation of protein kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

P

Seeded From UniProt

complete

involved_in

GO:0001707

mesoderm formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9DBC7
ensembl:ENSMUSP00000102288

P

Seeded From UniProt

complete

involved_in

GO:0001932

regulation of protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012198

P

Seeded From UniProt

complete

part_of

GO:0005952

cAMP-dependent protein kinase complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012198

C

Seeded From UniProt

complete

enables

GO:0008603

cAMP-dependent protein kinase regulator activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012198

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

enables

GO:0030552

cAMP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0116

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page