CHICK:JAK2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	JAK2
Protein Name(s)	Tyrosine-protein kinase JAK2 Janus kinase 2 JAK-2
External Links
UniProt	Q75R65
EMBL	AB159042
RefSeq	NP_001025709.1
UniGene	Gga.954
ProteinModelPortal	Q75R65
SMR	Q75R65
STRING	9031.ENSGALP00000037587
PaxDb	Q75R65
GeneID	374199
KEGG	gga:374199
CTD	3717
eggNOG	COG0515
HOGENOM	HOG000049158
HOVERGEN	HBG006195
InParanoid	Q75R65
KO	K04447
PhylomeDB	Q75R65
NextBio	20813703
PRO	PR:Q75R65
Proteomes	UP000000539
GO	GO:0005856 GO:0012505 GO:0016020 GO:0005634 GO:0005524 GO:0020037 GO:0042393 GO:0035401 GO:0004715 GO:0004713 GO:0042977 GO:0019221 GO:0030218 GO:0035409 GO:0060397 GO:0046777 GO:0007165
Gene3D	3.30.505.10
InterPro	IPR019749 IPR019748 IPR000299 IPR011009 IPR000719 IPR017441 IPR001245 IPR000980 IPR008266 IPR020635 IPR016251 IPR020693
Pfam	PF07714 PF00017
PIRSF	PIRSF000636
PRINTS	PR01823 PR01825 PR00109
SMART	SM00295 SM00252 SM00219
SUPFAM	SSF47031 SSF55550 SSF56112
PROSITE	PS50057 PS00107 PS50011 PS00109 PS50001

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0060397	growth hormone receptor signaling pathway via JAK-STAT	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q62120	P		Seeded From UniProt	complete
involved_in	GO:0046777	protein autophosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q62120	P		Seeded From UniProt	complete
involved_in	GO:0042976	activation of Janus kinase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q62120	P		Seeded From UniProt	complete
enables	GO:0042393	histone binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60674	F		Seeded From UniProt	complete
involved_in	GO:0035409	histone H3-Y41 phosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60674	P		Seeded From UniProt	complete
enables	GO:0035401	histone kinase activity (H3-Y41 specific)	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60674	F		Seeded From UniProt	complete
involved_in	GO:0030218	erythrocyte differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q62120	P		Seeded From UniProt	complete
enables	GO:0020037	heme binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60674	F		Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q62120	P		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q62120	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O60674	C		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q62120	F		Seeded From UniProt	complete
involved_in	GO:0030218	erythrocyte differentiation		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96629 PANTHER:PTN002401049	P		Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96629 MGI:MGI:99928 PANTHER:PTN002401049 RGD:2940 UniProtKB:O60674	P		Seeded From UniProt	complete
involved_in	GO:0007260	tyrosine phosphorylation of STAT protein		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96629 PANTHER:PTN002401049 RGD:2939	P		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR008266	F		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020635	F		Seeded From UniProt	complete
enables	GO:0004715	non-membrane spanning protein tyrosine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016251 InterPro:IPR020693	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR016251 InterPro:IPR017441 InterPro:IPR020693	F		Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000299	C		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR008266 InterPro:IPR016251 InterPro:IPR020635 InterPro:IPR020693	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016251 InterPro:IPR020693	C		Seeded From UniProt	complete
involved_in	GO:0035556	intracellular signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016251 InterPro:IPR020693	P		Seeded From UniProt	complete
enables	GO:0042393	histone binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020693	F		Seeded From UniProt	complete
enables	GO:0004715	non-membrane spanning protein tyrosine kinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.10.2	F		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0829	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0006325	chromatin organization	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0156	P		Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0147	C		Seeded From UniProt	complete
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References

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