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CHICK:ITF2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) TCF4
Protein Name(s) Transcription factor 4

TCF-4 Class A helix-loop-helix transcription factor GE2

External Links
UniProt Q90683
EMBL U35054
UniGene Gga.771
ProteinModelPortal Q90683
PaxDb Q90683
eggNOG NOG282899
HOGENOM HOG000234180
InParanoid Q90683
PhylomeDB Q90683
Proteomes UP000000539
GO GO:0005634
GO:0070888
GO:0046982
GO:0045666
GO:0006355
GO:0006351
Gene3D 4.10.280.10
InterPro IPR011598
Pfam PF00010
SMART SM00353
SUPFAM SSF47459
PROSITE PS50888

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0070888

E-box binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60722

F

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60722

F

Seeded From UniProt

complete

involved_in

GO:0045666

positive regulation of neuron differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q60722

P

Seeded From UniProt

complete

enables

GO:0043425

bHLH transcription factor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000927455
RGD:620914
RGD:69271
UniProtKB:P15923
UniProtKB:Q99081
WB:WBGene00001949

F

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:98510
PANTHER:PTN000927455
UniProtKB:P15923
WB:WBGene00001949

F

Seeded From UniProt

complete

part_of

GO:0005667

transcription factor complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:101877
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
RGD:620914
UniProtKB:P15923
UniProtKB:Q70IK3

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
RGD:3829
UniProtKB:P15884
UniProtKB:P15923
UniProtKB:Q99081
WB:WBGene00001949

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:98510
PANTHER:PTN000927455
UniProtKB:P15884
UniProtKB:P15923
UniProtKB:Q99081

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
UniProtKB:P15884
UniProtKB:P15923
UniProtKB:Q99081

F

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:101877
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
UniProtKB:P15923
UniProtKB:Q70IK3
WB:WBGene00001949

F

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267821
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455
RGD:3829
RGD:69271
UniProtKB:P15923
UniProtKB:Q99081
WB:WBGene00001949

P

Seeded From UniProt

complete

involved_in

GO:0045666

positive regulation of neuron differentiation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101877
MGI:MGI:98506
MGI:MGI:98510
PANTHER:PTN000927455

P

Seeded From UniProt

complete

enables

GO:0046983

protein dimerization activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011598
InterPro:IPR036638

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page